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Breast cancer metabolism - cross talk between different cell types within the breast

This project aims to investigate potential interaction the different cell types within the mammary gland. more...

Supervisor(s): Hoy, Andrew (Dr)

Design of new metal-based anti-cancer drugs

This project aims to investigate the mode of action of metal anti-cancer drugs, including both anti-metastatic and cytotocities against a range of different cancer cell lines.  more...

Supervisor(s): Lay, Peter (Professor)

Protein and peptide biomarkers of myocardial ischemia

This project will identify novel biomarkers (diagnostics) of ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

The role of calcium overload in myocardial ischemia / reperfusion injury

This project aims to identify the biochemical targets of calcium overload responsible for ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

Targeting melanoma secretory pathways.

Cancer cells secrete a variety of factors that induce tumour growth, metastasis, angiogenesis, and alter the tumour stroma to create a more favourable microenviroment. This project more...

Supervisor(s): Weninger , Wolfgang (Professor), Beaumont, Kimberley (Dr)

Taking proteomics to the clinic – biomarker and pathway analysis of patient samples

Only approximately 50% of patients will be successfully diagnosed by genetic analysis and even when a gene is identified, there may be no immediate drug target. Proteomics analysis more...

Supervisor(s): Graham, Mark (Dr)

Implantable Medical Devices

The ability to attach functional proteins, antibodies and enzymes to surfaces underpins the development of the next generation of implantable medical devices, biosensors and protein more...

Supervisor(s): Bilek, Marcela (Professor)

Identification of proteins specific to transmissible Pseudomonas aeruginosa in cystic fibrosis infection

This project will characterize the molecular basis for increased infectivity caused by an epidemic strain of Pseudomonas aeruginosa (AES-1) which infects many patients treated in cy more...

Supervisor(s): Cordwell, Stuart (Professor)

Post-translational modifications in bacterial proteins

This project will identify novel proteins that are post-translationally modified in bacterial pathogens and the role of such modification in virulence. more...

Supervisor(s): Cordwell, Stuart (Professor)

From the molecular study of receptor-ligand interactions to novel biomarkers of disease and non-invasive brain imaging - opportunities in basic and clinically oriented research

Methodologically broad but thematically focused on the role of receptors in glial (non-neuronal) cells in brain disease, the available basic science projects are concerned with the more...

Supervisor(s): Banati, Richard (Professor)