Your Search Results

GENES AND CELL-CELL INTERACTIONS IN CANCER PROGRESSION..

Oncogenes, tumour suppressor genes and cell-cell interactions in cancer: which are important in driving tumour progression and invasion in squamous cell carcinomas? more...

Supervisor(s): Lyons, Guy (Associate Professor)

Dendritic cells and control of T cell immune responses

DCs are unique antigen-presenting cells that can initiate (prime) CD4 T cell responses, as well as controlling the progression and subsequent reduction of the immune response, devel more...

Supervisor(s): Fazekas, Barbara (Professor)

New epidermal growth factor receptor (EGFR) inhibitors for the treatment of cancer

Molecular modelling and synthesis and characterisation of the hit compounds, biological testing in cell based assays and the determination of the inhibition of receptor dimerisation more...

Supervisor(s): Hibbs, David (Dai) (Professor)

REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)

Cancer Stem Cells

Cancer stem cell research more...

Supervisor(s): Hebbard, Lionel (Dr)

Medicinal and Pharmaceutical Chemistry — Design, Synthesis and Testing of Novel Anti-Cancer Agents

Are you interested in applying your laboratory expertise to the development of new drugs for cancer and other diseases?  Become part of a multi-disciplinary team involved in dr more...

Supervisor(s): Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)

The transformation of normal melanocytes into melanoma

This project investigates the role of the oncogenes Ras and Braf and the tumour suppressors p16INK4a, p14ARF, p53 and PTEN in the malignant transformation of melanocytes. more...

Supervisor(s): Kefford, Richard (Professor)

Biology of Dipeptidyl Peptidase IV and related proteins

Research projects centre on mouse models of liver disease and obesity and on the delineation of inhibitors, substrates, biochemistry and in vivo expression and function of the Dipep more...

Supervisor(s): Gorrell, Mark (Associate Professor)

Development of novel anti-cancer metastasis agents derived from omega-3 fatty acid metabolites

At present we have no therapies that prevent cancer spread. In this project we will develop novel w-3 fatty acid epoxide analogues that inhibit tumour metastasis. These derivatives more...

Supervisor(s): Murray, Michael (Professor)