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Muscle specific kinase in synaptic adaptation

This project will investigate the role of postsynaptic Muscle specific Kinase (MuSK) in regulating presynaptic neurotransmitter release at the neuromuscular junction. more...

Supervisor(s): Phillips, William (Bill) (Associate Professor), Protti, Dario (Dr)

Synaptic signalling therapies for anti-acetylcholine receptor myasthenia gravis

This project will use a mouse model to test potential treatments for the autoimmune disease, anti-acetylcholine receptor myasthenia gravis. more...

Supervisor(s): Phillips, William (Bill) (Associate Professor)

A cell culture model for Muscle Specific Kinase myasthenia gravis

The postsynaptic membrane of the neuromuscular junction (NMJ) is organized by Muscle specific tyrosine kinase (MuSK). This project will investigate the mechanisms that organize the more...

Supervisor(s): Phillips, William (Bill) (Associate Professor)

Targeting melanoma secretory pathways.

Cancer cells secrete a variety of factors that induce tumour growth, metastasis, angiogenesis, and alter the tumour stroma to create a more favourable microenviroment. This project more...

Supervisor(s): Weninger , Wolfgang (Professor), Beaumont, Kimberley (Dr)

Strengthening brittle bones

Osteogenesis imperfecta (OI) or "brittle bone disease" can be caused by a range of proteins involved with the bone matrix. Children with OI are prone to fracture, which can reduce m more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Little, David (Professor), Munns, Craig (Associate Professor)

Adiponectin and its role in wound healing

This project will use mouse models to investigate the role of adiponectin and its receptors in liver fibrosis. more...

Supervisor(s): Hebbard, Lionel (Dr)

Studies of a novel cancer gene with links to transcription

This project will investigate how a tumour suppressor implicated in a number of different malignancies functions to cause cancer. more...

Supervisor(s): Marsh, Deborah (Associate Professor)

Molecular genetics of plant development

Genes and gene networks involved in plant development. more...

Supervisor(s): Byrne, Mary (Associate Professor)

Mouse models of liver cancer

This project will use mouse models to investigate the role of adiponectin and T-cadherin in models of liver cancer. more...

Supervisor(s): Hebbard, Lionel (Dr), Qiao, Liang (Dr)

A Novel Approach of Inhibiting Pancreatic Cancer Metastasis via Targeting Tumour Micro-Environment Induced Autophagy

Targeting autophagy and metastasis in pancreatic cancer via NDRG1 Pancreatic Cancer (PC) is highly metastatic with the highest mortality of all cancers (~93%). The pancreatic tu more...

Supervisor(s): Sahni, Sumit (Dr)