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Refining cell-based therapies to cure diabetes

The most promising route for a cure for type 1 diabetes is the use of insulin-secreting cells to replace those that have died. more...

Supervisor(s): Thorn, Peter (Professor)

Towards a cure for Type I diabetes mellitus

Transfect a lentivirus construct expressing an immunosuppressive peptide in islet cells for the treatment of diabetes type I more...

Supervisor(s): Manolios, Nicholas (Professor), Logan, Grant (Dr)

Dysregulation of the inflammatory response in diabetes: Its role in poor wound healing

Diabetes is known to alter inflammatroy response but how this contributes to poor wound healing and other complications of diabetes is not known and will be investigated in this wor more...

Supervisor(s): McLennan, Susan (Dr), Shackel, Nicholas (Dr)

Mechanism of the effect of diabetes on the inflammation and subsequent fibrosis

In our laboratory we are investigating the effects of diabetes on the inflammatory response and the initiation of fibrosis and the relationship between these changes and the develop more...

Supervisor(s): McLennan, Susan (Dr)

Molecular studies of thyroid cancer and cutaneous squamous cell carcinoma

Identification of novel genes and miRNAs as predictors of thyroid cancer progression. more...

Supervisor(s): McLennan, Susan (Dr)

Investigation of the role of microRNAs in cell differentiation

Investigating the role of microRNAs in the regulation of stem cell multipotency and differentiation. more...

Supervisor(s): Rasko, John (Professor)

The role of miRNAs in diabetic renal interstitial fibrosis

The central aim of the project is to define the therapeutic benefit of targeting miRNAs in renal interstitial fibrosis in diabetic nephropathy. more...

Supervisor(s): Pollock, Carol (Professor), Chen, Xin-Ming (Dr)

Tubular autophagy in diabetic nephropathy

The central aim of the project is to define the role of autophagy dysfunction leading to renal tubulointerstitial fibrosis in diabetic nephropathy. more...

Supervisor(s): Pollock, Carol (Professor), Chen, Xin-Ming (Dr)

Functional Brain Image Understanding for Differential Diagnosis of Dementia

Intelligent analysis of functional brain images and extraction of pathologic patterns from large-group study for early diagnosis of dementia types more...

Supervisor(s): Feng, David (Professor), Xia, Yong (Dr)

REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)