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Social networks model for Open Source Drug Discovery

Using an open source drug discovery approach, current research shows that it is possible to find an improved synthesis of drugs for diseases (e.g. a tropical neglected disease such more...

Supervisor(s): Chung, Kenneth (Dr)

Drug Discovery and Medicinal Chemistry for the Central Nervous System

Projects involve developing novel CNS drugs through applications of organic synthesis, medicinal chemistry and pharmacological screening. more...

Supervisor(s): Kassiou, Michael (Professor)

Structure-based drug design with Soluble Epoxide Hydrolase

Soluble Epoxide Hydrolase (sEH), and more importantly its inhibition, may form the basis of a number of therapies due to anti-inflammatory more...

Supervisor(s): Church, W Bret (Dr)

Medicinal and Pharmaceutical Chemistry — Design, Synthesis and Testing of Novel Anti-Cancer Agents

Are you interested in applying your laboratory expertise to the development of new drugs for cancer and other diseases?  Become part of a multi-disciplinary team involved in dr more...

Supervisor(s): Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)

Informatics and Bioinformatics-based Approaches to Protein-Ligand Interaction

The principles of soluble protein structure and ligand docking are applied to structure analysis of membrane bound protein receptors and receptor ligand complexes. more...

Supervisor(s): Church, W Bret (Dr)

How do gingipains recognise their host cell targets?

Porphyromonas gingivalis is a gram-negative, rod-shaped anaerobic pathogenic bacterium that found in the oral cavity. more...

Supervisor(s): Collyer, Charles (Associate Professor)

Taking proteomics to the clinic – biomarker and pathway analysis of patient samples

Only approximately 50% of patients will be successfully diagnosed by genetic analysis and even when a gene is identified, there may be no immediate drug target. Proteomics analysis more...

Supervisor(s): Graham, Mark (Dr)

THE USE OF MARIJUANA AND/OR ENDOCANNABINOID OILS FOR THE TREATMENT OF OSTEOARTHRITIS (OA)

Pre-clinical studies for the effects of CBD and analogues for the treatment of osteoarthritis more...

Supervisor(s): Manolios, Nicholas (Professor), Arnold, Jonathon (Associate Professor)

Medicinal and Pharmaceutical Chemistry — Design, Synthesis and Testing of New Anti-Bacterial Agents

This project would appeal to those with interests in pharmaceutical applications of medicinal and protein chemistry. more...

Supervisor(s): Groundwater, Paul (Professor), Church, W Bret (Dr), Hibbs, David (Dai) (Professor)

Design of new metal-based anti-cancer drugs

This project aims to investigate the mode of action of metal anti-cancer drugs, including both anti-metastatic and cytotocities against a range of different cancer cell lines.  more...

Supervisor(s): Lay, Peter (Professor)