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Interplay between Innate and adaptive immunity in kidney ischemia reperfusion injury and allograft rejection

This study is to investigate the link between innate and adaptive immunity in kidney ischemia reperfusion injury and allograft rejection with a view to identifying new therapeutic t more...

Supervisor(s): Chadban, Steve (Professor), Wu, Huiling (Associate Professor)

Preventing rejection of transplanted organs without using immunosuppressive drugs

The project aims to identify molecular pathways to prevent rejection of transplanted organs in animal models and to apply these findings to clinical transplantation. more...

Supervisor(s): Bishop, Alex (Dr)

Interactions between porcine ligands and the human lymphocyte activating receptor NKG2D

Role of NKG2D in the human cellular immune response against porcine xenotransplants. more...

Supervisor(s): Sharland, Alexandra (Dr)

The role of miRNAs in diabetic renal interstitial fibrosis

The central aim of the project is to define the therapeutic benefit of targeting miRNAs in renal interstitial fibrosis in diabetic nephropathy. more...

Supervisor(s): Pollock, Carol (Professor), Chen, Xin-Ming (Dr)

Tubular autophagy in diabetic nephropathy

The central aim of the project is to define the role of autophagy dysfunction leading to renal tubulointerstitial fibrosis in diabetic nephropathy. more...

Supervisor(s): Pollock, Carol (Professor), Chen, Xin-Ming (Dr)