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Precision medicines for GABA-A receptor variants in epilepsy

Developmental and Epileptic Encephalopathies (DEEs) are rare and severe neurological conditions often associated with intellectual disability, developmental delay, autism spectrum d more...

Supervisor(s): Collins, Mary (Professor)

ENGINEERED EXTRASYNAPTIC GABAA RECEPTORS: TOWARDS NOVEL ANALGESICS

Recently, there has been an increase of interest in α4δ-containing GABAA receptors as novel drug targets for the design of a new class of analgesics. However, to date th more...

Supervisor(s): Balle, Thomas (Associate Professor), Collins, Mary (Professor)

The therapeutic potential of oxytocin in alcohol related harms

Alcohol is the most widely abused recreational drug in the world and arguably the most harmful. Acute alcohol intoxication can result in disability or death through alcohol related more...

Supervisor(s): McGregor, Iain (Professor)