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Molecular Dynamics of Glutamate Transporters

The aim of this project is to develop a molecular model for the mechanism of glutamate transport and through this we expect to identify novel means of pharmacologically manipulating more...

Supervisor(s): Ryan, Renae (Associate Professor)

Absolute quantification of Glutamate and GABA using proton magnetic resonance spectroscopy

The Department of Psychological Medicine at Royal North Shore Hospital undertakes neuroimaging research into cognitive functioning and underlying brain processes in neuropsychiatric more...

Supervisor(s): Lagopoulos, Jim (Associate Professor)

Elucidating the neural mechanisms of stress: a 13C-NMR study of glutamate and neuronal-glial interactions

13C-Magnetic Resonance Spectroscopy (13C-MRS) is an emerging imaging modality that allows the measurement of concentrations and synthesis rates of glutamate, glutamine and GABA with more...

Supervisor(s): Lagopoulos, Jim (Associate Professor)

Can brain neurochemicals distinguish headache types and pain types?

An opportunity exists for a PhD scholarship to investigate whether brain neurochemicals can distinguish between headache types and pain types. Work undertaken by our research team t more...

Supervisor(s): Rebbeck, Trudy (Dr), Refshauge, Kathryn (Professor)

How do molecules make memories? Understanding synaptic plasticity at the level of protein pathways and signalling.

This project aims to discover and validate new molecular mechanisms of how synaptic plasticity, which underlies learning and memory, is regulated by protein interactions and phospho more...

Supervisor(s): Graham, Mark (Dr)

Structure-based drug design with Kynurenine Aminotransferase-2

Human kynurenine amino transferase-2 (KAT-2) forms the basis of a structure-based drug design study with implications for schizophrenia and gender differences.  The various asp more...

Supervisor(s): Church, W Bret (Dr)