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Will a novel form of oral peanut immunotherapy induce regulatory immune responses and modify the gastrointestinal microbiome ?

In this part of the study, we will investigate the immunological mechanisms involved in the desensitization process. This will include the effects of short chained fatty acids in th more...

Supervisor(s): Nanan, Ralph (Professor)

Studies in Cell-Projection Pumping

Cell-projection pumping (CPP) is a mechanism we have recently discovered whereby cells pump cytoplasm between each other. We have discovered this in context of cancer, where there i more...

Supervisor(s): Zoellner, Hans (Professor)

Control of complement cascade by labile disulphide bonds

The complement system is a key component of innate immunity that offers sophisticated protection against threats to the host organism. Complement is also an important component of t more...

Supervisor(s): Chiu, Joyce (Dr)

An investigation into the mechanisms of immune evasion in metastatic melanoma patients treated with molecular or immune checkpoint inhibitors.

The aim of this project is to characterise the immune reaction and prevalence of immune inhibitory mechanisms present in metastatic melanoma patient tumours whilst on immune checkpo more...

Supervisor(s): Scolyer, Richard (Professor), Long, Georgina (Professor)

Viral Commandeering of Cellular Oncogenic Signalling Pathways

Cell-to-cell spread of caccinia virus infection induces dramatic rearrangements to cell morphology and alterations to cell behaviour.  This project will study the role of host more...

Supervisor(s): Newsome, Timothy (Dr)

Mechanisms of T cell migration and interactions in the tumor microenvironment

The project will use intravital two-photon microscopy to determine the molecules involved in interstitial T cell migration and the molecular mechanisms of T cell interactions with t more...

Supervisor(s): Weninger , Wolfgang (Professor)

Defining the clinical and immunogenetic profile in antibody-associated demyelination

Masters or PhD opportunity ideally suited for a medical or neurology trainee or fellow with a commitment to building expertise in clinical and translational neuroimmunology. more...

Supervisor(s): Ramanathan, Sudarshini (Dr), Brilot-Turville, Fabienne (Dr), Dale, Russell (Professor)

The anti-apoptotic activity of serum albumin for endothelial cells

Earlier work in my laboratory, established that serum albumin contains a cryptic protein domain that is exposed through transient intra-molecular protein movement, to bind a G-prote more...

Supervisor(s): Zoellner, Hans (Professor)

Studies in the biophysics of dentine and dental caries

Although dental caries remains the world's most common infectious disease, current concepts of caries pathogenesis are based on microscopic methods now many decades old. Treatment w more...

Supervisor(s): Zoellner, Hans (Professor)

Dental robotics

Robotic dental surgery offers significant clinical advantages, but has not yet been developed. We are exploring development of dental robotics in collaboration with the Faculty of E more...

Supervisor(s): Zoellner, Hans (Professor)