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Phosphate homeostasis and fungal virulence

Inorganic phosphate (Pi) is an important macronutrient for all living organisms including yeast, and is essential for ATP, phospholipid and protein synthesis, metabolism and signall more...

Supervisor(s): Djordjevic, Julianne (Dr), Sorrell, Tania (Professor)

Design of Novel Biosensors and Microfluidic Devices for Interrogating the Insulin Signalling Pathway

The aim of this project is to design, engineer and validate novel biosensors that can be used to interrogate the insulin signalling pathway in live cells. more...

Supervisor(s): James, David (Professor)

The role of redox in signalling: assessing the requirement of reactive oxygen species in signal transduction

Define the role of ROS in insulin signal transduction and explore how loss of control of this process causes diseases such as diabetes and cancer more...

Supervisor(s): James, David (Professor)

Synaptic signalling therapies for anti-acetylcholine receptor myasthenia gravis

This project will use a mouse model to test potential treatments for the autoimmune disease, anti-acetylcholine receptor myasthenia gravis. more...

Supervisor(s): Phillips, William (Bill) (Associate Professor)

A cell culture model for Muscle Specific Kinase myasthenia gravis

The postsynaptic membrane of the neuromuscular junction (NMJ) is organized by Muscle specific tyrosine kinase (MuSK). This project will investigate the mechanisms that organize the more...

Supervisor(s): Phillips, William (Bill) (Associate Professor)

Solute Carrier Transporters

PhD project is available in this laboratory on investigating the relationship of human drug transporters with drugs in treating prevalent diseases such as diabetes and cancers. more...

Supervisor(s): Zhou, Fanfan (Dr)

Chemical synthesis and phenotypic validation of precision proteolysis targeted chimeras (PROTACs) for cancer and cardiovascular disease

Emerging from the interface between chemistry and biology, chemical biology has led to the establishment of several game-changing drug discovery paradigms. Among these revolutionary more...

Supervisor(s): Liu, Xuyu (Dr), Payne, Richard (Professor)

Kinetic Characterization and Mapping for Whole-body Molecular Image Retrieval

In vivo kinetic behaviour characterization and dynamic holistic mapping for efficient dual-modality whole-body molecular imaging data retrieval. more...

Supervisor(s): Feng, David (Professor), Cai, Tom Weidong (Associate Professor)