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Prostate cancer metabolism – investigating the role of lipid metabolism and the microenvironment

This project aims to investigate potential interaction the different cell types near the prostate gland and how changes in androgen signalling alters this relationship. It also aims more...

Supervisor(s): Hoy, Andrew (Dr)

Bioactive Lipid Modulation of Glycine Transporters and Glycine Receptors

A major focus of our work is on the design, synthesis and development of new bioactive lipids that inhibit glycine transporters. These compounds represent a new class of allosteric more...

Supervisor(s): Vandenberg, Robert (Professor)

The Role of the Osteoblast in Mediating Glucocorticoid-Induced Metabolic Dysfunction

To investigate how glucocorticoid affect the regulation of glucose and lipid metabolism. more...

Supervisor(s): Zhou, Hong (Professor), Seibel, Markus (Professor)

Breast cancer metabolism - cross talk between different cell types within the breast

This project aims to investigate potential interaction the different cell types within the mammary gland. more...

Supervisor(s): Hoy, Andrew (Dr)

Developing small molecules that enhance PCSK9/AnxA2 interaction to inhibit PCSK9 and elevate LDLR levels

Statins to decrease low density lipoprotein cholesterol (LDL-C) are a cornerstone to prevent and treat cardiovascular events. However, inadequate dose response, resistance, and seri more...

Supervisor(s): Grewal , Thomas (Associate Professor)

Prevalence and impact of incorrect cancer research publications targeting the functions of human genes

This PhD project analyses the reliability of the cancer research literature, from which new cancer biomarkers and molecular targets are derived. more...

Supervisor(s): Byrne, Jennifer (Professor)

LDL-cholesterol controls the role of integrins in cancer cell migration

This project explores the role of LDL-cholesterol in integrin trafficking and signalling, which is relevant for cancer cell migration. more...

Supervisor(s): Grewal , Thomas (Associate Professor)

The role of calcium overload in myocardial ischemia / reperfusion injury

This project aims to identify the biochemical targets of calcium overload responsible for ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

Early signs of diabetes complications in childhood onset diabetes mellitus

Early signs of diabetes complications in childhood onset diabetes will focus on newer methods to assess heart rate variation, peripheral nerve function, colour vision and vascular c more...

Supervisor(s): Donaghue, Kim (Professor)

Protecting the heart from ischaemia-reperfusion injury: a new role for FXYD proteins?

We are interested to have a PhD student join our team at the Kolling Institute, examining the therapeutic potential of FXYD proteins in a model of heart attack/myocardial infarction more...

Supervisor(s): Figtree, Gemma (Associate Professor)