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Prostate cancer metabolism – investigating the role of lipid metabolism and the microenvironment

This project aims to investigate potential interaction the different cell types near the prostate gland and how changes in androgen signalling alters this relationship. It also aims more...

Supervisor(s): Hoy, Andrew (Dr)

Breast cancer metabolism - cross talk between different cell types within the breast

This project aims to investigate potential interaction the different cell types within the mammary gland. more...

Supervisor(s): Hoy, Andrew (Dr)

The Role of the Osteoblast in Mediating Glucocorticoid-Induced Metabolic Dysfunction

To investigate how glucocorticoid affect the regulation of glucose and lipid metabolism. more...

Supervisor(s): Zhou, Hong (Professor), Seibel, Markus (Professor)

Molecular Mechanism of Insulin Resistance

Insulin resistance is a major physiological problem that is associated with an inability of insulin to regulate glucose and lipid metabolism. We now know that metabolism is central more...

Supervisor(s): James, David (Professor)

Discovery and validation of new ceramide synthase inhibitors to treat metabolic disease

Ceramide synthase enzyme isoforms 1, 5, and 6, are heavily implicated as drivers of obesity, insulin resistance, and diabetes. Targeting these enzymes is expected to yield new thera more...

Supervisor(s): Don, Anthony (Associate Professor), Qi, Jacob (Dr)

Insulin-mediated regulation of adipocyte lipolysis

Insulin, a hormone that is released after a meal, regulates many aspects of metabolism including a process called lipolysis that involves the release of fatty acids into the circula more...

Supervisor(s): James, David (Professor)

Dissecting the architecture of the Insulin Signaling Pathway

The aim of this pathway is to understand how the insulin signalling pathway regulates metabolic homeostasis.The Lead Supervisor for this project is David James. This project will a more...

Supervisor(s): James, David (Professor)

Prevalence and impact of incorrect cancer research publications targeting the functions of human genes

This PhD project analyses the reliability of the cancer research literature, from which new cancer biomarkers and molecular targets are derived. more...

Supervisor(s): Byrne, Jennifer (Professor)