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Interaction of viral and tuberculosis infections in the lung

This project will examine how two of the most important respiratory pathogens of humans, Influenza and Tuberculosis, interact and stimulate protective immune responses in the lungs. more...

Supervisor(s): Britton, Warwick J (Professor)

Identification of proteins specific to transmissible Pseudomonas aeruginosa in cystic fibrosis infection

This project will characterize the molecular basis for increased infectivity caused by an epidemic strain of Pseudomonas aeruginosa (AES-1) which infects many patients treated in cy more...

Supervisor(s): Cordwell, Stuart (Professor)

The molecular basis of persistence in clinical P. aeruginosa strains from cystic fibrosis patients

Pseudomonas aeruginosa, the leading cause of morbidity and mortality in people with cystic fibrosis (CF), adapts to survive in the CF lung through both mutation and gene expression more...

Supervisor(s): Manos, Jim (Dr), Triccas, Jamie (Dr)

Novel inhalation formulation to improve quality of life of cystic fibrosis sufferers

Respiratory infection is the number one cause of death world-wide with limited therapies other than tablet or intravenous injection. This multi-faceted PhD project will focus on dev more...

Supervisor(s): Traini, Daniela (Professor)

Regulation of host resistance and immune response to human pathogens

The laboratory of Immunology and Host Defense focuses on the immune mechanisms that regulate host resistance to pathogens of global importance. It currently offers multiple projects more...

Supervisor(s): Feng, Carl (Dr)

Combination antibiotics powder aerosols for treatment of respiratory infections

This project aims to develop and characterise novel powder aerosol formulations of the combination antibiotics for treatment of respiratory infections. Respiratory infections are ex more...

Supervisor(s): Chan, Kim (Professor)

Regulation of ion transport in the respiratory epithelium in health and disease

The project will focus on elucidating the mechanisms by which respiratory pathogens including influenza, parainfluenza, avian influenza (H5N1) viruses, and microbacterium tuberculos more...

Supervisor(s): Cook, David I (Professor)

Novel delivery systems for the development of tuberculosis vaccines

This project aims to develop new generation vaccines to combat tuberculosis. more...

Supervisor(s): Triccas, Jamie (Dr), Britton, Warwick J (Professor)

To identify new mechanisms used by pathogenic mycobacteria to secrete virulence proteins

This project aims to identify new mechanisms employed by pathogenic mycobacteria to secrete virulence proteins into the extracellular environment more...

Supervisor(s): Triccas, Jamie (Dr)

Investigation of virulence genes upregulated in coinfection between P. aeruginosa and other species

Identify the set of genes diffrentially expressed when P. aeruginosa is grown in coculture with three other infecting species. Select genes with virulence/persistence characteristic more...

Supervisor(s): Manos, Jim (Dr)