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Targeting melanoma secretory pathways.

Cancer cells secrete a variety of factors that induce tumour growth, metastasis, angiogenesis, and alter the tumour stroma to create a more favourable microenviroment. This project more...

Supervisor(s): Weninger , Wolfgang (Professor), Beaumont, Kimberley (Dr)

An investigation into the mechanisms of immune evasion in metastatic melanoma patients treated with molecular or immune checkpoint inhibitors.

The aim of this project is to characterise the immune reaction and prevalence of immune inhibitory mechanisms present in metastatic melanoma patient tumours whilst on immune checkpo more...

Supervisor(s): Scolyer, Richard (Professor), Long, Georgina (Professor)

IMPROVING MELANOMA PREVENTION, EARLY DETECTION, AND CLINICAL MANAGEMENT

PhD and Masters research projects could include:- Analysis of epidemiological or clinical data related to skin cancer risk factors, health outcomes or clinical practice guidelines- more...

Supervisor(s): Cust, Anne (Professor)

The transformation of normal melanocytes into melanoma

This project investigates the role of the oncogenes Ras and Braf and the tumour suppressors p16INK4a, p14ARF, p53 and PTEN in the malignant transformation of melanocytes. more...

Supervisor(s): Kefford, Richard (Professor)

Dynamic prediction of longitudinal markers and time to disease progression in metastatic melanoma patients

This project aims to develop individualised dynamic event prediction models, combining simultaneously longitudinal biomarker data and time-to-event data. more...

Supervisor(s): Lo, Serigne (Dr), Long, Georgina (Professor)

Sleep and Cancer: The role of intermittent hypoxia

Background: Recent epidemiological studies have shown that patients with obstructive sleep apnoea (OSA) have higher rates of cancer and cancer mortality however the underlying mecha more...

Supervisor(s): Cook, Kristina (Dr), Cistulli, Peter (Professor)

Role of Vitamin D and other compounds in protection of skin cells from UV

This study examines how vitamin D compounds protect skin from sun or UV-induced DNA and other damage. more...

Supervisor(s): Mason, Rebecca (Professor)

Molecular Dynamics of Glutamate Transporters

The aim of this project is to develop a molecular model for the mechanism of glutamate transport and through this we expect to identify novel means of pharmacologically manipulating more...

Supervisor(s): Ryan, Renae (Associate Professor)

Patient preferences and willingness to pay for genomic information in cancer and cardiovascular disease

It is not clear how people value genetic or genomic health information, and traditional economic evaluation may not capture the full benefit of this service. This PhD will examine p more...

Supervisor(s): Morton, Rachael (Associate Professor)

Molecular studies of thyroid cancer and cutaneous squamous cell carcinoma

Identification of novel genes and miRNAs as predictors of thyroid cancer progression. more...

Supervisor(s): McLennan, Susan (Dr)