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Development of novel anti-cancer metastasis agents derived from omega-3 fatty acid metabolites

At present we have no therapies that prevent cancer spread. In this project we will develop novel w-3 fatty acid epoxide analogues that inhibit tumour metastasis. These derivatives more...

Supervisor(s): Murray, Michael (Professor)

Absolute quantification of Glutamate and GABA using proton magnetic resonance spectroscopy

The Department of Psychological Medicine at Royal North Shore Hospital undertakes neuroimaging research into cognitive functioning and underlying brain processes in neuropsychiatric more...

Supervisor(s): Lagopoulos, Jim (Associate Professor)

Structure-based drug design with Soluble Epoxide Hydrolase

Soluble Epoxide Hydrolase (sEH), and more importantly its inhibition, may form the basis of a number of therapies due to anti-inflammatory more...

Supervisor(s): Church, W Bret (Dr)

A Novel Approach of Inhibiting Pancreatic Cancer Metastasis via Targeting Tumour Micro-Environment Induced Autophagy

Targeting autophagy and metastasis in pancreatic cancer via NDRG1 Pancreatic Cancer (PC) is highly metastatic with the highest mortality of all cancers (~93%). The pancreatic tu more...

Supervisor(s): Sahni, Sumit (Dr)