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Molecular investigations of receptors involved in neurological disorders

The Laboratory of Molecular Neuroscience investigates molecular regulation and drug interactions that occur in receptors associated with neurological diseases. more...

Supervisor(s): Holsinger, Damian (Dr)

An investigation into the mechanisms of immune evasion in metastatic melanoma patients treated with molecular or immune checkpoint inhibitors.

The aim of this project is to characterise the immune reaction and prevalence of immune inhibitory mechanisms present in metastatic melanoma patient tumours whilst on immune checkpo more...

Supervisor(s): Scolyer, Richard (Professor), Long, Georgina (Professor)

Molecular and genetic basis of heart disease

The main focus of our research is the study of genetic heart disorders, which includes new gene discovery, genotype-phenotype correlation studies, and understanding the underlying p more...

Supervisor(s): Semsarian, Christopher (Professor)

Control of cell differentiation during mouse embryogenesis and stem cell development

The research will provide insights into how progenitor cells for embryonic tissues may be specified and determine the conditions that promote differentiation into germ layer derivat more...

Supervisor(s): Tam, Patrick (Professor)

REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)

Medicinal Chemistry and Biology - Development of Novel Anti-Tumour Agents for Cancer Treatment

This project is involved in the exciting development of novel drugs for the treatment of cancer and other conditions. more...

Supervisor(s): Richardson, Des (Professor)

The Role of Extracellular Matrix Metalloprotease Inducer (EMMPRIN) in Liver Disease

The role of the hepatocyte in progressive liver injury. more...

Supervisor(s): Shackel, Nicholas (Dr)

GENES AND CELL-CELL INTERACTIONS IN CANCER PROGRESSION..

Oncogenes, tumour suppressor genes and cell-cell interactions in cancer: which are important in driving tumour progression and invasion in squamous cell carcinomas? more...

Supervisor(s): Lyons, Guy (Associate Professor)

Stem Cells in Liver Disease

The role of stem cells in progressive liver injury. more...

Supervisor(s): Shackel, Nicholas (Dr)

Investigating the links between telomerase and the DNA damage response in cancer cells

The ribonucleoprotein enzyme telomerase counteracts telomere shortening in a majority of cancers, allowing for unlimited cell division. Most normal cells do not express telomerase, more...

Supervisor(s): Bryan, Tracy (Professor)