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REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)

Amino acid sensing mechanisms in human biology.

Amino acid sensing mechanisms determine how dietary protein regulates appetite and satiety, how feeding influences endocrine responses and how nutrition can direct cell fate in brea more...

Supervisor(s): Conigrave, Arthur (Professor)

From the molecular study of receptor-ligand interactions to novel biomarkers of disease and non-invasive brain imaging - opportunities in basic and clinically oriented research

Methodologically broad but thematically focused on the role of receptors in glial (non-neuronal) cells in brain disease, the available basic science projects are concerned with the more...

Supervisor(s): Banati, Richard (Professor)

Interactions between porcine ligands and the human lymphocyte activating receptor NKG2D

Role of NKG2D in the human cellular immune response against porcine xenotransplants. more...

Supervisor(s): Sharland, Alexandra (Dr)

Molecular investigations of receptors involved in neurological disorders

The Laboratory of Molecular Neuroscience investigates molecular regulation and drug interactions that occur in receptors associated with neurological diseases. more...

Supervisor(s): Holsinger, Damian (Dr)

Towards a cure for Type I diabetes mellitus

Transfect a lentivirus construct expressing an immunosuppressive peptide in islet cells for the treatment of diabetes type I more...

Supervisor(s): Manolios, Nicholas (Professor), Logan, Grant (Dr)

Molecular Dynamics of Glutamate Transporters

The aim of this project is to develop a molecular model for the mechanism of glutamate transport and through this we expect to identify novel means of pharmacologically manipulating more...

Supervisor(s): Ryan, Renae (Associate Professor)

The Role of PPAR gamma in thyroid cancer

Differentiation therapy for thyroid cancer by targeting the fusion gene PAX8-PPARgamma. more...

Supervisor(s): Clifton-Bligh, Roderick (Dr)

Genetic control of resistance and susceptibility to tuberculosis

Both environmental and genetic factors influence susceptibility to tuberculosis; this project will identify and investigate polymorphisms in genes that may increase susceptibility t more...

Supervisor(s): Saunders, Bernadette (Dr)

Mechanisms of T cell migration and interactions in the tumor microenvironment

The project will use intravital two-photon microscopy to determine the molecules involved in interstitial T cell migration and the molecular mechanisms of T cell interactions with t more...

Supervisor(s): Weninger , Wolfgang (Professor)