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Drug Discovery and Medicinal Chemistry for the Central Nervous System

Projects involve developing novel CNS drugs through applications of organic synthesis, medicinal chemistry and pharmacological screening. more...

Supervisor(s): Kassiou, Michael (Professor)

Combined, Correlative and Integrated Microscopy: Unraveling Biomolecular Structure-Function Activities in Cancer & Transendothelial Transport

Our team seek to understand the spatial and temporal mechanisms involved in the onset and progress of colorectal cancer by using state-of-the-art multidimensional microscopy and 3-D more...

Supervisor(s): Braet, Filip (Associate Professor)

Mapping genes for nerve disease

Our laboratory has an exemplary track record for mapping genes for inherited peripheral neuropathies. Charcot-Marie-Tooth (CMT) neuropathy is a degenerative disorder of the peripher more...

Supervisor(s): Kennerson, Marina (Associate Professor), Nicholson, Garth (Professor)

Fluorescent sensors for oxidative stress

Oxidative stress is associated with all diseases of ageing, and there is therefore a need for better tools to identify and quantify the condition. We are developing novel fluorescen more...

Supervisor(s): New, Elizabeth (Associate Professor)

The role of calcium overload in myocardial ischemia / reperfusion injury

This project aims to identify the biochemical targets of calcium overload responsible for ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

Plasmonics for Protein Attachment

Plasmonics will be used in combination with ellipsometry to investigate the attachment of biomolecules to surfaces. The structure of the attached layers will be investigated using n more...

Supervisor(s): McKenzie, David (Professor)

Understanding how Flaviviruses interact with the host immune system to cause disease

This laboratory is investigating the interaction of neurotropic Flaviviruses with the vertebrate host immune system to discover how it causes immune-mediated disease (immunopatholog more...

Supervisor(s): King, Nicholas (Professor)

Chemical Biology of Siderophores

Studies of bacterial metal-management strategies have implications for treating iron overload disease and for better understanding bacterial pathogenic virulence. more...

Supervisor(s): Codd, Rachel (Dr)

Magnetic resonance micro-imaging of human and animal tissue.

Use of magnetic resonance microimaging of human and animal tissue to study disease processes. more...

Supervisor(s): Bourne, Roger (Dr)