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How invasive cancer cells negotiate the 3D tissue environment

My team uses cell biology approaches to discover the cellular machinery that allows deadly, invasive cancer cells to negotiate the surronding 3D environment. more...

Supervisor(s): O'Neill, Geraldine (Associate Professor)

Sleep and Cancer: The role of intermittent hypoxia

Background: Recent epidemiological studies have shown that patients with obstructive sleep apnoea (OSA) have higher rates of cancer and cancer mortality however the underlying mecha more...

Supervisor(s): Cook, Kristina (Dr), Cistulli, Peter (Professor)

The DNA replication stress response

Genome integrity in human cells is maintained through the coordinated functions of the DNA damage response. We study these processes with particular interest in the pathways that re more...

Supervisor(s): Cesare, Tony (Dr)