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Cellular mechanisms of opioid tolerance and dependence

Tolerance and dependence that contribute to opioid addiction will be studied using patch clamp analyses of cellular and synaptic electrophysiology in brain slices and behavioural co more...

Supervisor(s): Christie, Macdonald (Professor)

Unravelling mechanisms determining the balance between tolerance and immunity in the liver

Role of primary T cell activation in the liver in CD8 T cell tolerance more...

Supervisor(s): Bertolino, Patrick (Dr)

Healing and Self-Repair in Large Scale Distributed Computing Systems

The project will focus on the development of fault tolerance mechanisms to allow distributed systems to operate under different operating conditions. more...

Supervisor(s): Zomaya, Albert Y. (Professor)

Preventing rejection of transplanted organs without using immunosuppressive drugs

The project aims to identify molecular pathways to prevent rejection of transplanted organs in animal models and to apply these findings to clinical transplantation. more...

Supervisor(s): Bishop, Alex (Dr)

Dendritic cells and control of T cell immune responses

DCs are unique antigen-presenting cells that can initiate (prime) CD4 T cell responses, as well as controlling the progression and subsequent reduction of the immune response, devel more...

Supervisor(s): Fazekas, Barbara (Professor)

Regulatory T cells

Regulatory T cells (Tregs) control autoimmune, allergic and inflammatory responses, and are involved in organ transplantation and immune responses to cancer. more...

Supervisor(s): Fazekas, Barbara (Professor)

Interactions between porcine ligands and the human lymphocyte activating receptor NKG2D

Role of NKG2D in the human cellular immune response against porcine xenotransplants. more...

Supervisor(s): Sharland, Alexandra (Dr)

How do Australian plants cope with phosphorus deficiency?

Determine how Australian native plants can cope with phosphorus deficiency more...

Supervisor(s): Warren, Charles (Associate Professor)

Developing Molecular biomarkers in sleep disorders

This project will explore potential biomarkers for a range of sleep disorders including obstructive sleep apnoea, insomnia and circadian phase disorders. more...

Supervisor(s): Phillips, Craig (Dr), Grunstein, Ron (Professor)