About Dr Karren Plain

Karren joined the Farm Animal and Veterinary Public Health group as a Research Fellow in 2007. Her work involves the analysis of differential gene expression in the host/pathogen interaction in Johne’s disease, identification of genetic resistance traits and development of techniques for early diagnose of infection.

Interests include understanding how the immune response is controlled in chronic infectious diseases. Without control, an immune response that is meant to protect may damage the normal tissues in the body. These principles have been applied to the study of Johne’s disease in sheep and cattle, a chronic disease where the infectious organism attempts to evade immune attack. One form of evasion may be by harnessing of immune regulatory mechanisms that have evolved to protect the host.

Dr Plain is a researcher in the Sydney School of Veteriary Science. For more information about Dr Plain, please refer to her Academic Profile Online.