About Associate Professor Filip Braet

The application of multi-dimensional high-resolution correlative microscopy approaches to the biomedical field & Fishing for biomolecules in cancer nanobiology.

A/Prof Braet has 18 years' experience as a research cell and structural biologist, specialising in the use of microscopy and fine-structure techniques to explore stracture-function relationships. Following undergraduate, honours and masters studenies in medical technology and biomedical sciences, he began a doctorate on the ultrastructure of the liver endothelium in 1992 with Prof. E. Wisse at the Free University of Brussels. In 2002, he was appointed a Visting Professor of Life Sciences at his alma mater; a year later, he joined the Department for Molecular Biomedical Research, University Ghent. In 2004, he joined the University of Sydney. 
During the last decade, A/Prof Braet has been awarded over $5.75 million in competitive funds for research and reserach infastructure, with funding coming from European and other international sources, the ARC, the NHMRC, the Cancer Institute NSW, and universities. A/Prof Braet research has been awarded the Ignace Vanderschuere Prize for Biomedicine (2001) bu the Free University of Brussels, and the JAAME Award (2006, 2007 and 2008) by the Japan Association for the Advancement of Medical Equipment (JAAME). To date, he has successfully supervised 5 Ph.D. students and 22 master by research students, and is currently supervisor to two Ph.D. studetns and associate supervisor of another three. 

Selected publications

1.      Ty Truong W, Su Y, Meijer J, Thordarson P, Braet F. Self-assembled gels for biomedical applications. Chem Asian J 2011:6;30-42.
2.      Su Y, Nykanen M, Jahn KA, Whan R, Cantrill L, Soon LL, Ratinac KR, Braet F. Multi-dimensional correlative imaging of subcellular events: combining the strengths of light and electron microscopy. Biophys Rev 2010:2;121-135
3.      Su Y, Whan R, Empsen C, Soon L, Braet F. Multidimensional live cell imaging of cancer-mediated events. In: Méndez-Vilas A, D'az J, eds. Modern Research and Educational Topics in Microscopy (Vol IV). Badajoz, Formatex Press, 2010:1-12
4.      Braet F, Soon L, Vekemans K, Thordarson P, Spector I. Actin-binding drugs: An elegant tool to dissect subcellular processes in endothelial and cancer cells. In: Protein reviews, Volume 8 – Actin-binding proteins and disease. dos Remedios C, Chhabra D, eds. New York: Springer, 2008:37-49.
5.      Braet F, Soon L, Kelly TF, Larson J, Ringer SP. Some new advances and challenges in biological and biomedical materials characterisation. In: Kumar CSSR, ed. Nanotechnologies for the Life Sciences Vol 3 - Nanosystem Characterization Tools in the Life Sciences. Weinheim – Berlin: Wiley-VCH Verlag GmbH & Co. KgaA, 2006:292-318.
6.      Braet F, Wisse E. Imaging surface and submembranous structures in living cells with the atomic force microscope: notes and tricks. In: Braga PC, Ricci D, eds. Atomic Force Microscopy: Methods and Protocols in Biomedical Applications. Totowa, NJ: Humana Press Inc., 2004:201-216.
7.      Braet F, Luo D, Spector I, Vermijlen D, Wisse E. Endothelial and pit cells. In: Arias I, Boyer JL, Fausto N, Jakoby WB, Schachter DA, Schafritz DA, eds. The liver: Biology and Pathobiology, 4th ed. New York: Raven Press, 2001:437-453.
8.      Wisse E, Braet F, Dianzhong L, Vermijlen D, Eddouks M, Empsen C, Spapen H, De Zanger RB. Sinusoidal liver cells. In: Bircher J, Benhamou JP, McIntyre N, Rizzetto M, Rodés J, eds. Oxford Textbook of Clinical Hepatology, Volume 1. New York: Oxford University Press, 1999:33-49.
9.      Wisse E, Dianzhong L, Vermijlen D, Kanellopoulou C, De Zanger R, Braet F. On the function of pit cells, the liver-specific natural killer cells. Semin Liver Dis 1997:17;265-286.
10.  Smedsrød B, De Bleser PJ, Braet F, Lovisetti P, Vanderkerken K, Wisse E, Geerts A. Cell biology of liver endothelial and Kupffer cells. Gut 1994:35;1509-1516.