About Associate Professor Zoe McKeough

My area of research interest is in the management of respiratory disorders such as chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF) and dust-related lung disorders. I am particularly interested in exercise and physical activity assessment and the effectiveness of exercise interventions in these groups.

My expertise lies in the area of exercise testing and training in people with respiratory disorders, particularly COPD, where I have conducted physiological studies, observational studies and randomised controlled trials.

First, I have conducted a number of studies examining the assessment of exercise capacity in people with COPD including both arm and leg exercise capacity. In these studies I have examined the effects of various arm exercise tests such as the unsupported arm exercise test and determined how these relate to leg exercise testing such as cycle tests. I have also examined the best way to conduct walk tests such as the six minute walk test and endurance shuttle walk test. Secondly, I have examined the effectiveness of various exercise interventions in people with COPD including arm exercise interventions, Tai Chi training, aquatic therapy, walking training, training with oxygen supplementation and maintenance exercise training. Of particular interest in many of these studies is how well these interventions improve exercise capacity, physical activity and health-related quality of life. In the area of cystic fibrosis, I have been involved in studies examining exercise and physical activity assessment as well as examining the physiological effects of exercise on secretion clearance.

Selected publications

  • McKeough ZJ, Alison JA, Bye PT (2003)  Arm exercise capacity and dyspnea ratings in subjects with Chronic Obstructive Pulmonary Disease. Journal of Cardiopulmonary Rehabilitation 23: 218-225.
  • Ennis S, Alison J, McKeough Z (2009)  The effects of arm endurance and strength training on arm exercise capacity in people with chronic obstructive pulmonary disease. Physical Therapy Reviews 14:226-239.
  • Spencer LM, Alison JA, McKeough ZJ (2010)  Maintaining benefits following pulmonary rehabilitation: a randomised controlled trial. Eur Respir J 35:571-577.
  • Leung RWM, Alison JA, McKeough ZJ, Peters MJ (2010)  Ground walk training improves functional exercise capacity more than cycle training in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial. Journal of Physiotherapy 56: 105-112.
  • McKeough ZM, Leung RWM, Alison JA (2011)  Shuttle Walk Tests as Outcome Measures: Are two incremental shuttle walk tests and two endurance shuttle walk tests necessary? American Journal of Physical Medicine & Rehabilitation 90: 35-39.
  • McNamara RJ, Alison JA, McKeough ZJ (2011)  Water-based exercise in COPD. Phys Ther reviews 16: 25-30.
  • Dwyer T, Alison J, McKeough Z, Daviskas E, Bye P (2011)  Effects of exercise on respiratory flow and sputum properties in cystic fibrosis. Chest 139:870-877.
  • Dale MT, McKeough ZJ, Troosters T, Bye P, Alison JA (2011)  Exercise training to improve exercise capacity and quality of life in people with non-malignant dust-related respiratory diseases (Protocol). Cochrane Database of Systematic Reviews 2011, Issue 10. Art. No.:CD009385. DOI: 10.1002/14651858.CD009385.
  • McKeough ZJ, Bye PTP, Alison JA (2012)  Arm exercise training in Chronic Obstructive Pulmonary Disease: a randomised controlled trial. Chronic Respiratory Disease, 9(3), 153-162.
  • Leung RWM, McKeough ZJ, Peters MJ, Alison JA (2013)  Short-form Sun-style Tai Chi as an exercise training modality in people with COPD. European Respiratory Journal, 41(5), 1051-1057.