About Dr Marianne Weber

I work in the Cancer Research Division at Cancer Council NSW, which is a community-funded, evidence-based organisation with a strategic focus on cancer control in our local community. As such, the research we conduct has the unique and privileged ability to influence the action of policy makers, practitioners and the community directly to reduce the national and international impact of cancer. Everyone I know has been affected by cancer in one way or another and so being a part of the Cancer Council team, surrounded by people who are passionate about achieving a cancer-free future, is an inspiring place to conduct research.

The research we conduct internally at Cancer Council NSW has an overarching objective of identifying interventions in cancer control that have the greatest impact in reducing the burden of cancer. We have expertise in epidemiology, biostatistics, modelling, implementation science, and systematic review.

I lead a team of postgraduate students and postdoctoral research fellows who are building predictive models of lung cancer and smoking-related disease to evaluate the effectiveness and cost-effectiveness of interventions in tobacco control, lung cancer screening, and new and emerging lung cancer therapies.
A large component of my research uses the 45 and Up Study to estimate the impact of key exposures on cancer incidence, mortality and health services utilisation in Australia. The 45 and Up Study is the biggest cohort study ever undertaken in Australia and began in 2006. It contains demographic, health, and lifestyle information from ~267,000 individuals, aged 45 and over across NSW. Participants are being followed up both with 5-yearly questionnaires and via linkage to routinely collected administrative datasets, such as the NSW Cancer Registry.
My research has an epidemiology focus and has largely examined modifiable risk factors and determinants of three main cancer types: lung, colorectal, and prostate cancer. Identifying individuals and groups at a higher than average risk of cancer and cancer-specific mortality is of particular interest. I am part of a broader cancer research network which aims to address factors related to cancer incidence, care, and outcomes in the 45 and Up Study.
I have a background in Psychology and laboratory-based behavioural neuroscience. I have various publications on tobacco use, cancer screening, lung cancer patterns of care, and men's health. I am part of a network of expert clinicians and researchers from around Australia exploring the harms and benefits of lung cancer screening.

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Selected publications

Wade S, Weber M, Caruana M, Kang YJ, Marshall H, Manser R, Vinod S, Rankin N, Fong K, Canfell K. (2018) Estimating the Cost-Effectiveness of Lung Cancer Screening with Low-Dose Computed Tomography for High-Risk Smokers in Australia. J Thorac Oncol;13(8):1094-1105.

Goldsbury DE, Yap S, Weber MF, Veerman L, Rankin N, Banks E, Canfell K, O'Connell DL. (2018) Health services costs for cancer care in Australia: Estimates from the 45 and Up Study. PLoS One;13(7):e0201552

Weber M, Yap S, Goldsbury D, Manners D, Tammemagi M, Marshall H, Brims F, McWilliams A, Fong K, Kang YJ, Caruana M, Banks E, Canfell K. (2017) Identifying high risk individuals for targeted lung cancer screening: Independent validation of the PLCOm2012 risk prediction tool. Int J Cancer;141(2):242-253.

Yu XQ, Luo Q, Kahn C, Cahill C, Weber M, Grogan P, Jemal A, O'Connell DL. (2017) Widening socioeconomic disparity in lung cancer incidence among men in New South Wales, Australia, 1987-2011. Chin J Cancer Res. 29(5):395-401

Kricker A, Weber M, Sitas F, Banks E, Rahman B, Goumas C, Kabir A, Hodgkinson VS, van Kemenade CH, Waterboer T, Armstrong BK. (2017) Early Life UV and Risk of Basal and Squamous Cell Carcinoma in New South Wales, Australia. Photochem Photobiol; 93(6):1483-1491.

Banks E, Joshy G, Weber MF, Liu B, Grenfell R, Egger S, Paige E, Lopez AD, Sitas F, Beral V. (2015) Tobacco smoking and all-cause mortality in a large Australian cohort study: findings from a mature epidemic with current low smoking prevalence. BMC Med; 13:38.

Steffen A, Weber MF, Roder DM, Banks E. (2014) Colorectal cancer screening and subsequent incidence of colorectal cancer: results from the 45 and Up Study. Med J Aust; 201(9):523-7.

Weber MF, Smith DP, O'Connell DL, Patel MI, de Souza PL, Sitas F, Banks E. (2013) Risk factors for erectile dysfunction in a cohort of 108 477 Australian men. Med J Aust; 199(2):107-11.

Weber MF, Cunich M, Smith DP, Salkeld G, Sitas F, O'Connell D. (2013) Sociodemographic and health-related predictors of self-reported mammogram, faecal occult blood test and prostate specific antigen test use in a large Australian study. BMC Public Health; 13:429

For a full list of Dr Weber's publications please see her Research Gate profile page Research Gate Profile Page .