About Dr Tony Cesare

My laboratory studies how telomeres function in human cells to maintain genome integrity, and the molecular and cellular consequences when these processes fail.

The long-term goal of my laboratory is to understand the fundamental mechanisms used by human cells to maintain genome integrity, and how failures in these processes contribute to human disease. Currently, we are using our expertise in the field of telomere biology to study how changes in telomere structure relate to cell growth arrest in healthy cells, and conversely how changes in telomere structure cooperate with the loss of tumor suppressors to promote genomic instability and cancer. As our research base and technical capacity grows, we anticipate using our ability to modulate telomere biology as a model to study fundamental mechanisms of genome protection in human cells.

Dr. Cesare is an early career independent researcher and a Cancer Institute NSW Future Research Leader. He assumed his role as head of the CMRI Genome Integrity Group in June 2013 and became a conjoint Senior Lecturer at the University of Sydney later that year. Prior to this he was a post-doctoral fellow with Prof. Jan Karlseder at the prestigious Salk Institute in La Jolla, California (8/2009 – 6/2013), and with Prof. Roger Reddel at CMRI (1/2006 – 4/2009). He completed his Ph. D. in the United States with Prof. Jack Griffith at the University of North Carolina at Chapel Hill (12/2005).

Selected publications

For a full list of Dr. Cesare's publications please see his academic profile page