About Dr Grant Hill-Cawthorne

Infectious diseases and medical microbiology are undergoing the most significant shift since PCR was introduced. By the end of this decade, sequencing will have become the main option when investigating any outbreak or infection. I study the interface between genomics as a pure science and its translation into clinical and public health benefits.

Grant has made important contributions in the field of genomics, particularly its use for public health microbiology. Prior to his interest in genomics, he worked in the field of neuroimmunology, working on a newly emerging drug for multiple sclerosis, alemtuzumab. He first demonstrated how the immune system reconstitutes following CD52 ablation, which was used as the first human model of homeostatic T-cell proliferation. Whilst working for NICE, Grant was the Clinical Advisor to the National Chronic Hepatitis B Guideline Development Group, co-developing a network meta-analysis model of CHB drug treatment and developing this into a cost effectiveness model. Since 2010 he has focused on microbiology genomics, leading two large-scale studies, one into global epidemiology of Mycobacterium tuberculosis (published in Nature Genetics) and one on the evolution of the BCG vaccine (published in NPG Scientific Reports). Since moving to the University of Sydney, Grant has coordinated several genomics studies into outbreaks of Listeria and TB, infant cases of botulism, TB epidemiology in Pakistan, Mongolia, Portugal and South Africa; and a paediatric outbreak of cholera in India. He has published over 44 peer-reviewed publications and has been cited nearly 2200 times with an h-index of 21 (Google Scholar).

Grant is Head of the Parliamentary Office of Science and Technology, UK Parliament and Adjunct Associate Professor of Global Health at the University of Sydney. He was previously the Clinical Advisor to the Deputy Chief Executive of the National Institute for Health and Care Excellence, UK. Grant received his undergraduate degree from the University of Cambridge, UK (2004) followed by his medical degree (2007) and MA (2009) from the same institution. He then worked within academic clinical positions at teaching hospitals of the University of Cambridge before being appointed Academic Clinical Fellow and Specialty Registrar in Medical Virology at the University of East Anglia in 2009. In 2010 he was seconded to the King Abdullah University of Science and Technology to design and build a pathogen genomics laboratory, during which time he completed his PhD (2015). In 2011 he was invited to be the NHS Medical Director's National Clinical Fellow and Clinical Advisor to NICE, where he worked full-time for 18 months while continuing his PhD part-time. In January 2013, Grant moved to the University of Sydney as a joint appointment between the School of Public Health and the newly established Marie Bashir Institute for Infectious Diseases and Biosecurity (MBI). Since 2015 he has been the co-leader of the Mass Gathering Medicine node of MBI. In 2018 Grant moved back to the UK to head the academic unit that bridges research and policy for the House of Commons and House of Lords.

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Selected publications

For a full list of Dr. Hill-Cawthorne's publications please see his Academic Profile Page