About Dr Jim Manos

I have a passionate desire to make a major contribution to the field of microbial pathogenesis in cystic fibrosis.

Dr Jim Manos is a microbial biologist analyzing the virulence characteristics of the human pathogen Pseudomonas aeruginosa.

Dr Manos has established a track record in the field of Gram negative bacterial pathogenesis over the past 12 years and leads his own research team as Head of the Bacterial Pathogens in Cystic Fibrosis Group at the Sydney Medical School where he has focused on the molecular characterisation of Pseudomonas aeruginosa strains infecting the lung environment of cystic fibrosis patients. Since his appointment as Lecturer in 2007, he has established strong collaborations with other leading researchers within the Pseudomonas field as well as in the broader scientific community with experts in the fields of genomics and proteomics. His collaborators include Associate Professor Cynthia Whitchurch (UTS, Sydney) a leading Pseudomonas researcher, Associate Professor Stuart Cordwell (Sydney University) internationally renowned expert in proteomics research (NHMRC#632788 2010), Dr Scott Beatson (University of Queensland) innovative genomics expert (ACFRT Grant 2009) and Dr James Triccas (Sydney University) a leading scientist in Mycobacterium tuberculosis research. He also has close collaborative relationships with leading hospital-based researchers in P. aeruginosa. Dr Manos' research in Gram negative pathogens has led to high quality publications in peer reviewed journals. His most significant publications in the P. aeruginosa field include:

  • The first transcriptomic analyses of the highly infective and virulent Australian Epidemic Strains AES-1 and AES-2 (Manos et al 2008 and Manos et al 2009).
  •  The first validation for use of an Artificial Sputum Medium (ASMDM) (Fung et al 2010).

Selected publications

For a comprehensive list of Dr Manos's publicatons, please visit his Sydney Medical School profile page.