About Dr Alex Bishop

Organ transplantation is a straightforward solution to a life or death problem but untangling the threads of why transplants are rejected and how to avoid rejection is a fascinating and intricate process.

Dr Alex Bishop is known nationally and internationally for his work on transplantation tolerance and rejection and heads a group investigating ways to prevent rejection that minimise use of powerful and dangerous immunosuppressive drugs

Dr Bishop has devoted his research career to the immunology of transplantation and is well known nationally and internationally for his work in the field. For the last fifteen years he has been investigating the mechanism of transplant acceptance and rejection in small animal models, in particular, a model of liver transplant tolerance. He is the foremost world expert in this area as shown by his invitations to speak internationally and invited reviews on the subject. His team was the first to observe that activation of the immune system accompanied tolerance, work that contributed to the demise of the paradigm that Th1 and Th2 pathways were responsible for rejection and acceptance, respectively. His group went on to be the first to break acceptance of liver transplants, by reducing the donor leucocytes in the transplanted liver. This work has been highly cited and has led to many invitations to speak at international and national scientific meetings. He is an editorial board member of the international journal Transplantation and has been a national councilor of the Transplantation Society of Australia and New Zealand. He regularly receives requests to review articles for journals such as Nature Medicine, Liver Transplantation, American Journal of Transplantation and Biotechniques.

Selected publications

For a comprehensive list of Professor Bishop's publicatons, please visit his Sydney Medical School profile page.