About Professor Helen Reddel

Professor Reddel is a Research Leader at the Woolcock Institute of Medical Research, University of Sydney and Clinical Adviser for the Australian Centre for Airways disease Monitoring (ACAM). She is internationally recognised for her research and leadership in management of airways disease, including through her role as Chair of the Science Committee of the Global Initiative for Asthma. Her current research includes strategies for identifying and reducing risk in mild asthma, including investigation of patterns of symptoms, lung function and medication use; underlying mechanisms in asthma and COPD; a large Australian population study about breathlessness; qualitative research in mild and severe asthma. She has a strong focus on improving communication between patients and health professionals, and on making guidelines not only evidence-based, but also practical, and patient-centred.

20 years’ experience in conducting randomised controlled trials, pragmatic cluster studies, observational studies and qualitative studies

Since 2017, Professor Reddel has published four papers in New England Journal of Medicine and three papers in Lancet. She led a recent evidence-based change to the paradigm of asthma management, described in a 2019 editorial in European Respiratory Journal. Her pharmacy-based research on practical strategies to improve inhaler technique led to a change in asthma guidelines. She is currently international co-chair of a large study investigating trajectories and underlying mechanisms in asthma and COPD.

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Selected publications

1. Wong A, Hardaker K, Field P, et al. Home-based forced oscillation technique day-to-day variability in pediatric asthma. Am J Respir Crit Care Med. 2019;199:1156-60.
2. Reddel HK, Gerhardsson de Verdier M, Agusti A, Anderson G, Beasley R, Bel EH, Janson C, Make B, Martin RJ, Pavord I, Price D, Keen C, Gardev A, Rennard S, Svereus A, Bansal AT, Brannman L, Karlsson N, Nuevo J, Nyberg F, Young SS, Vestbo J. Prospective observational study in patients with obstructive lung disease: NOVELTY design. ERJ Open Research 2019; 5: 00036-02018.
3. Reddel HK, FitzGerald JM, Bateman ED, Bacharier LB, Becker A, Brusselle G, Buhl R, Cruz AA, Fleming L, Inoue H, Ko FW, Krishnan JA, Levy ML, Lin J, Pedersen SE, Sheikh A, Yorgancioglu A, Boulet LP. GINA 2019: a fundamental change in asthma management: Treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents. Eur Respir J 2019; 53.
4. Reddel HK, Beckert L, Moran A, Ingham T, Ampon RD, Peters MJ, Sawyer SM. Is higher population-level use of ICS/LABA combination associated with better asthma outcomes? Cross-sectional surveys of nationally representative populations in New Zealand and Australia. Respirology 2017; 22: 1570-1578.
5. O'Byrne PM, FitzGerald JM, Bateman ED, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Ivanov S, Reddel HK. Inhaled combined budesonide-formoterol as needed in mild asthma. N Engl J Med 2018; 378: 1865-1876.
6. Davis SR, Tudball J, Flynn A, Lembke K, Zwar N, Reddel HK. "You've got to breathe, you know" - asthma patients and carers' perceptions around purchase and use of asthma preventer medicines. Aust N Z J Public Health 2019; 43: 207-213.
7. Laba TL, Jan S, Zwar NA, Roughead E, Marks GB, Flynn AW, Goldman MD, Heaney A, Lembke KA, Reddel HK. Cost-related underuse of medicines for asthma-opportunities for improving adherence. The journal of allergy and clinical immunology In practice 2019.
8. Foster JM, Usherwood T, Smith L, et al. Inhaler reminders improve adherence with controller treatment in primary care patients with asthma. J Allergy Clin Immunol. 2014;134:1260-8.
9. Foster JM, McDonald VM, Guo M, Reddel Helen K. "I have lost in every facet of my life": the hidden burden of severe asthma. Eur Respir J 2017; 50: 1700765.
10. Hew M, Reddel HK. Integrated adherence monitoring for inhaler medications. JAMA. 2019;321:1045-6.