Skip to main content

Reducing non-steroidal anti-inflammatory drug use in people with knee osteoarthritis

An assessment of feasibility and acceptability of a repeated measures study for risk minimisation
This study will evaluate a novel intervention to help people reduce their reliance on pain medication for management of knee osteoarthritis.

Research shows that physiotherapy delivered exercise and healthy lifestyle changes are beneficial in reducing pain and improving function in people with knee osteoarthritis. Participation in this study will involve an initial monitoring phase lasting 6 weeks, followed by a physiotherapy intervention over 12 weeks. The intervention will involve consultations with a physiotherapist using video-conferencing technology, and involve exercise, pain management strategies and coaching for reducing your pain medication. 


To be eligible to participate in this study you need to:

  • Be aged ≥ 45 years 
  • Have knee pain
  • Regularly use non-steroidal anti-inflammatory drug (e.g. Nurofen, voltaren and celecoxib) 
  • Have access to the Internet

You will not be eligible for the study if you have:

  • A chronic inflammatory condition (e.g. rheumatoid arthritis)
  • A condition that affects your ability to walk (e.g. Parkinson’s disease)
  • Unstable cardiovascular condition (e.g. unstable angina)
  • Regular use of strong opioids (e.g. morphine)
  • Knee replacement surgery on both knees or on your most painful knee
  • Been involved in a structured exercise program or a group exercise program designed by a physiotherapist to manage your knee pain (this does NOT include personal trainer sessions, group gym exercise programs, walking) 

Ethics committee approval number: 2018/973 

How to participate

If you are interested in assisting with this study, please follow this link to check your eligibility and register your interest here. Alternatively, please call +61 2 8627 0030.