Understanding the function of biomolecular structures holds the key to a wide range applications from biotechnology to pharmacology and medicine, and in our computational biophysics group this is our main focus.
Physicists have a lot to contribute to this area which requires modeling of biological systems at different time scales using quantum, classical and stochastic dynamics. Judicious modeling that links vastly different space-time domains (e.g. nano and micro domains) is essential in achieving useful answers.
Therefore, our focus is to develop hierarchical schemes that will allow description of biomolecular processes with the available computational resources. The methods involved - from most phenomenological to fundamental - are:
Most of the projects require substantial computational power and we make use of the supercomputers in Sydney (AC3) and Canberra (APAC).