04/2017 – present Senior Lecturer / Head ForeFront Bioinformatics & Statistics Research Group, Brain & Mind Center, University of Sydney
12/2013 – present Conjoint Lecturer Faculty of Medicine, University of New South Wales.
07/2013 – 02/2017 Bioinformatics Research Officer in Neuroscience with Prof. A Cooper & Prof. JS Mattick at the Garvan Institute of Medical Research in Sydney: “Functional characterization of the complete human brain transcriptome from Parkinson’s disease associated loci.”
09/2008 – 03/2013 PhD in Nucleic Acid Research & Medicinal Chemistry with Dr. H Towbin & Prof. J Hall at the Department of Chemistry and Applied Biosciences at ETH Zurich/Switzerland: “Synthesis-enabled strategies to identify new microRNA biology”.
01/2008 – 07/2008 Diploma theses in Immunology and generating a knock-in mouse with Prof. D Vestweber at the Max Planck Institute for Molecular Biomedicine: “VE-Cadherin mediated regulation of endothelial cell-cell contacts”.
09/2003 – 07/2008 Chemistry Diploma in Muenster/Germany.
I am a research scientist/bioinformatician/statistician specializing in the development of infrastructure, software and pipelines to manage, analyze and mine large complex datasets in medical research. Using structured, semi-structured and unstructured data, my research focuses on the identification and characterization of genetic variation and transcriptional changes influencing complex human diseases (such as frontotemporal lobe dementia, bipolar disorder, Parkinson’s and Alzheimer’s disease, etc.). I achieve this through the functional integration of high-dimensional biological (omics) data, in combination with my statistical, genetics and data mining skills. I believe that assimilating and modelling multi-modal data (i.e. imaging, clinical and omic data) is key to uncovering the genotype-phenotype interaction and how this relationship affects complex traits.
Conjoint Lecturer Faculty of Medicine, University of New South Wales
Visiting Scientist, Garvan Institute of Medical Research
Bioinformatics Lead ICPGC
02/2016 Invited talk at the Data Science Sydney Meetinghttps://youtu.be/z5Wz3jKk12E 05/2016 Invited talk at Sydney Capital Markets CRC brown bag seminar series.
10/2015 Invited workshop “Current methodologies in transcriptome analysis”. Federal University of Minas Gerais, Belo Horizonte, Brazil.
10/2015 Invited workshop Bioinformatics & Computational Biology X-Meeting 2015 Sao Paulo, Brazil. 08/2015 Finalist Parkinson’s NSW Young Researcher of the Year Award.
03/2015 Keystone Symposia Scholarship & Invited talk: “Long Noncoding RNAs: From Evolution to Function.”
09/2014 8thA+PD Symposium Sydney, Best poster
01/2014 – 01/2016 Early Postdoc Mobility Fellowship Swiss National Science Foundation (P2EZP3_152143).
01/2010 – 12/2012 Project Grant “Chemical biology in microRNA pathways.” Swiss National Science Foundation.
07/2003 – 09/2003 “European International Biotechnology School” in Perugia/Italy (scholarship EU).
- Mutations in genes causal of white matter disease and dys-regulation of lipid metabolism in frontotemporal dementias, Kwok J, Don A, Don A, Dobson-Stone C, Landin-Romero R, Kim W, Guennewig B, National Health and Medical Research Council (NHMRC)/Project Grants
In the media