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Cancer Elimination Collaboration

Collaborating to accelerate the elimination of all cancers
  • https://www.sydney.edu.au/medicine-health/industry-and-community/industry-partnerships/partnership-enquiries.html Partner with us
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Reducing cancer rates by half

The Cancer Elimination Collaboration develops and leverages partnerships to accelerate the elimination of all cancers.

Our interim goal is to cut cancer mortality rates in Australia by 50% by 2050 (“50 by 50”) and support cancer control in partner countries.

Title : Evidence translation

Description : We optimally use and equitably have access to established interventions which is key to fast-tracking improved cancer outcomes.

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Title : 50 by 50

Description : We are mapping a pathway to cut Australian cancer death rates by 50% by 2050 through bold but feasible goals.

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Title : Global collaborators

Description : Our researchers collaborate with an extensive local and global network of cancer researchers and institutes and measure success with published data.

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Our vision

The World Health Organization (WHO) strategy for eliminating cervical cancer shows that cancer elimination is feasible – for cervical cancer and, as evidence accrues, applying integrated strategies for the improved control and elimination of other cancers. How soon cancers are eliminated will depend on how quickly established and emerging technologies can be deployed, and how quickly the existing gaps in the evidence can be addressed.

Rapid translation of evidence-based approaches will also be the key to averting deaths from cancer, aselimination strategies and evidence evolve.

Our aim is to accelerate progress towards eliminating cancers by working with partners to:

  • Publish new evidence, geared towards “best buys” in cancer control for population-wide benefit,
  • Research and promote the integration of cancer prevention, early detection, referral, treatment and support into health systems for optimal outcomes
  • Foster a cancer-literate community, with increasing awareness of opportunities in implementing established evidence into practice and the benefits of population-level interventions in cancer prevention, early detection and referral to treatment,
  • Predict, map and monitor cancer control outcomes such as incidence, mortality, stage at diagnosis, recurrence and quality of life, to identify challenges and successes, track progress and inform optimal targeting of research,
  • Utilise epidemiology, scenario modelling, health services/implementation science research and economic analyses to inform best cases for cancer control investment,
  • Work with government and non-government organisations worldwide to promote the translation of evidence into sustainable policy and practice, including through clinical practice guidelines, and
  • Support collaborators with complementary strengths in cancer control to promote synergistic approaches to working towards cancer elimination.

Projects

Elimination Partnership in the Indo-Pacific for Cervical Cancer (EPICC)

EPICC is a four-year initiative (2024-2028) supported by the Australian Government and the Minderoo Foundation.

The program responds to the WHO 3-pillar global strategy to eliminate cervical cancer, bringing together a consortium of leading Australian cancer research and implementation partners with global partners and Ministries of Health in the Indo-Pacific region to advance their national cervical cancer elimination strategies. 

The program provides a comprehensive suite of tailored, evidence-based support, working with governments to augment existing plans and priorities.

Partner countries include Papua New Guinea, Malaysia, Timor-Leste, Solomon Islands, Vanuatu, Tuvalu, Fiji and Nauru.

The Elimination Partnership in the Indo-Pacific for Cervical Cancer (EPICC) consortium is led by the University of Sydney and includes the Australian Centre for the Prevention of Cervical Cancer (ACPCC), the Kirby Institute at UNSW Sydney, Family Planning Australia (FPA), the National Centre for Immunisation Research and Surveillance (NCIRS), and UNITAID.

Consortium partners lead activities in their areas of expertise.

The EPICC program also collaborates with global and national partners with expertise and networks in cancer treatment, secondary prevention of cervical cancer, and HPV vaccination.

Global implementing partners include; the Union for International Cancer Control (UICC), the International Gynaecologic Cancer Society (IGCS), and the National Cancer Institute (NCI/NHI).

Elimination Planning Tool (EPT)

The Cervical Cancer Elimination Planning Tool (EPT) was developed by our team at the University of Sydney and the International Agency for Research on Cancer, with funding from Cancer Research UK’s International Cancer Prevention programme.

The tool was developed as part of the work of the International Partnership for Resilience in Cancer Systems (I-PaRCS). 

It received strategic input from an international expert reference group and builds on prior work by the Cervical Cancer Elimination Modelling Consortium (CCEMC), which supported the 2020 WHO strategic plan.

The EPT incorporates updated estimates from the Policy1-Cervix model, developed over 23 years by the University of Sydney team, to evaluate the impact of HPV vaccination, screening, and treatment in low-resource settings. 

  • International Agency for Research on Cancer (IARC)
  • Cancer Research UK 

International Partnership for Resilience in Cancer Systems

The International Partnership for Resilience in Cancer Systems (I-PaRCS) is an initiative co-led by the Cancer Elimination Collaboration at the University of Sydney and the IARC Initiative for Resilience in Cancer Control (IRCC) which aims to bring together the global community to support decision-making in cancer control.

The partnership was originally formed as a response to the COVID-19 pandemic in early 2020, but has since broadened and evolved to address a wide range of themes related to the ongoing resilience of cancer systems.

Furthermore, this partnership connects teams from various countries, in a collaborative effort to strengthen cancer systems’ response to existing and emerging challenges, such as infectious diseases, conflicts, natural disasters, and other disruptions.

  • International Agency for Research on Cancer (IARC)
  • Union for International Cancer Control (UICC)
  • Canadian Partnership Against Cancer (CPAC)
  • International Cancer Screening Network (ICSN) 

Economic evaluation of expansion of command centre services into Aboriginal medical services in Western Australia

Since 2018, the Western Australia Country Health Service’s Command Centre (WACHS CC), a virtual clinical hub, has provided more than 160,000 video consultations to 88 emergency sites state-wide and have avoided hospital transfers for 74% of patients seen by their service.

This project looks to understand the economic costs, and service access benefits, of embedding the service into additional regional communities.

Funding: Digital Health Cooperative Research Centre

Reducing health literacy barriers to Heart Health Checks

This partnership project involves working with multiple stakeholders to codesign and implement heart health literacy solutions. It aims to reduce access barriers to preventive Heart Health Checks in primary care and close equity gaps in cardiovascular disease outcomes.

This includes evidence-based decision support for GPs and patients, behaviour change tools for people with lower health literacy, conversation guides to facilitate culturally appropriate shared decision making with Aboriginal and Torres Strait Islander communities, integration with GP and Primary Health Network programs and software systems, and testing new models of care for targeted risk screening in general practice.

The interventions have improved both GP and patient knowledge of CVD risk; increased healthy lifestyle behaviours, risk factor assessment and MBS billing for Heart Health Checks; reached over 100,000 people in the research phase and over 500,000 since being integrated into new guidelines and clinical risk assessment tools.

Funding: National Health and Medical Research Council, Heart Foundation, Royal Australian College of General Practitioners, Medical Research Future Fund via Prevention Centre, Department of Health and Aged Care.

Following is a snapshot of current research projects, in which the CEC is involved in either a leadership or a supporting role. For information about any of these projects, please email cec.coordinating-team@sydney.edu.au

  • Expanded report on emerging risk factors and interventions in early-onset cancers (Cancer Australia)
  • Cancer Council Australia Clinical Practice Guidelines Review
  • HPV self-sampling cost effectiveness model (UK – Health and Social Care)
  • Safety monitoring for the National Cervical Screening Program (Dept of Health)
  • The Opioid Cohort Consortium (OPICO) to investigate the effects of using opioids on cancer risk (USA – National Institute of Health)
  • Stronger Investments for Infectious Diseases (STRIDE) (NHMRC)
  • HPV screening in vaccinated populations: A clinical and cost-effectiveness model (UK – Health and Social Care) 
  • Max Up Trial maximising uptake of lung cancer screening and smoking cessation outcomes (Dept of Health) 
  • Centre for Research Excellence in Cervical Cancer Control (C4) (NHMRC)
  • CuRE Centre of Research Excellence to prevent and detect curable lung cancer (NHMRC) 
  • Consultancy to update the Unitaid Cervical Cancer screen and treat technology landscape (UNITAID)
  • Supporting Choice:  co-led by CEC and the University of Melbourne, this project is focussed on using HPV self-collection to improve equity and participation in Australia’s National Cervical Screening Program (NHMRC)
  • Screen Your Way: led by Yardhura Walani at the Australian National University, this project is focused on embedding community driven models to increase cervical screening among Aboriginal and Torres Strait Islander people and improve cervical cancer outcomes (NHMRC)
  • ScreenEQUAL: led by CEC, this project is trialling a co-produced suite of resources to support cervical screening with and for people with intellectual disability (NHMRC)
  • Enhancing Equity in Cervical Screening (EECS): co-led by CEC and  Centre of Disability Studies, this project is piloting a Disability Cervical Screening Advocates program and co-delivering cervical screening webinars for the disability sector (Department of Health, Disability and Ageing)
  • Genomic risk prediction and risk-tailored screening and early detection for common cancers (MRFF-funded research project.)
  • Optimising cardiovascular disease prevention for all Australians: Evidence and modelling for population-based screening and management (Ian Potter Foundation)
  • Effective implementation and scale-up of the World Health Organisation strategy to eliminate cervical cancer in Australia, the Indo-Pacific and globally (Investigator Grant NHMRC)
  • CISNET Cervix: Comparative modelling to inform cervical cancer control policies (US – National Cancer Institute/Harvard University) 
  • Equity and optimisation of cervical cancer prevention in women living with HIV: Advancing methods, impact, and accessibility (Cancer Institute NSW)
  • Evaluating primary HPV screening in select US-affiliated Pacific Islands (US – Centre for Disease Control)
  • Evaluating the potential of an innovative area of patient-friendly, non-invasive cancer screening in Australia: Multi-cancer early detection tests (MRFF-funded research project.) 
  • The provision of services to develop and deliver national information and awareness activities to support the National Lung Cancer Screening Program (Department of Health, Disability and Ageing)
  • SISTASCREEN: led by Southern Cross University, this project aims to co-design and implement strategies to increase uptake of opportunistic cervical screening during pregnancy and postpartum for First Nations women (Cancer Australia) 
  • International Partnership for Resilience in Cancer Systems (I-PaRCS) (International Agency for Research on Cancer)
  • Developing evidence-based Australian Clinical Practice Guidelines for the Management of Cervical Cancer (Dept of Health) [In collaboration with Cancer Council Australia]
  • The COMPASS trial, a randomised controlled trial to compare 2.5-yearly cytology-based cervical screening with 5-yearly primary HPV screening in Australian women aged 25-69 [Co-led by the Australian Centre for the Prevention of Cervical Cancer]
  • INCLUDE: led by the Kirby Institute, UNSW, this project focuses on creating a novel health equity digital navigation tool to generate and share cervical cancer prevention data on local populations with unacceptably high rates of cervical cancer, that can be immediately actioned by primary health care providers, consumers, and other end users across Australia ***
  • PREVENT: led by the University of Notre Dame, this project focuses on developing an effective same-day cervical screening model for Aboriginal communities in remote areas and leverages the CEC’s expertise in policy evaluation, as we look to the benefits of scaling this model up. 
  • CURVVE: led by QIMR Berghofer Medical Research Institute, this project focuses on answering questions about risk factors, diagnosis, prevention (vaccination & screening), patterns of care and survival for uterine, cervical, vaginal and vulvar cancer in Australia, using linked data.
  • Australian Cervical Cancer Evaluation (ACCE) Project: led by the Australian Centre for the Prevention of Cervical Cancer, this project focuses on understanding involved HPV types, histopathology, staging and screening history in people with cervical cancer, to enhance our understanding of the performance of cervical cancer prevention programs. 
  • Breast ROSA Project (Roadmap to Optimising Screening in Australia) (Australian Government/Cancer Council Australia)
  • Analysis of somatic mosaicism as a marker for cancer risk (MRFF-funded research project)
  • Contrast based imaging for breast cancer screening, staging and surveillance (in collaboration with Melbourne Health)
  • Breast cancer patient cohort analyses (in collaboration with Melbourne Health)
  • Modelled evaluations of the clinical and cost-effectiveness of various breast cancer control interventions (Various)
  • Info4Scope: a practical information source on colonoscopy for patients (Cancer Institute NSW)
  • Understanding colonoscopy access in NSW (Cancer Institute NSW)
  • Refer4Scope - Improving GP education for colonoscopy referral (Cancer Institute NSW)
  • MAIL, GP, and SCALE: Mobilising national bowel cancer screening program participation through combining individual, health service, and population level interventions (NHMRC)
  • Modelled evaluations of the health impact and cost-effectiveness of various colorectal cancer control interventions (Various)
  • Tackling Australia’s low screening participation to prevent bowel cancer morbidity and deaths: led by the University of Melbourne (NHRMC)
  • Optimising colorectal cancer screening in high-income countries and low-and-middle income countries using Australia and China as an example (NHMRC)
  • Co-producing cancer survivorship resources with and for people with intellectual disability: Led by Flinders University (MRFF) 
  • NGOR: Establishing a national, linked, clinical quality registry for cervical cancer, led by Monash University (MRFF) 
  • HPVTATE: Led by the Kirby Institute UNSW, the project aims to establish HPV-based testing and treatment for the elimination of cervical cancer in Papua New Guinea (GACD and NHMRC)

Our people

 

  • Ms Chloe Jennett
  • Harriet Hui
  • Amy Pagotto
  • Arina Ridha
  • Caitlin Rogers

  • Sally-Anne Byatt
  • Dr Surbhi Grover
  • Chloe Jennett
  • Tay Za Kyi Win

Lung cancer

  • Professor Kwun Fong
  • Associate Professor Henry Marshall
  • Dr Annette McWilliams

Gastrointestinal cancers

  • Professor Hooi Ee
  • Professor Jacob George
  • Professor Finlay Macrae

Breast cancer

  • Professor Bruce Mann
  • Dr Jill Evans

Cervical/HPV

  • Professor Marion Saville AM
  • Kate Broun

Other gynaecological cancers

  • Professor Anna de Fazio AM

Cancer prevention

  • Professor Emily Banks AM
  • Professor Andrew Wilson AO
  • Professor Becky Freeman
  • Professor Tim Driscoll
  • Associate Professor Maarit Laaksonen
  • Adjunct Associate Professor Craig Sinclair
  • Adjunct Professor Terry Slevin
  • Professor Maree Teesson

Health services

  • Professor Sanchia Aranda AM
  • Professor Louisa Collins
  • Professor David Goldstein
  • Professor Haryana Dhillon
  • Professor Jeff Dunn AO
  • Professor Rachel Neale
  • Professor Sarah Norris
  • Dr Meena Rafiq
  • Dr Diana Sarfati

First Nations

  • Professor Lisa Whop
  • Professor Gail Garvey AO
  • Associate Professor Raglan Maddox

Consumer engagement

  • Jeff Cuff
  • Annie Miller
  • Christine Whittall
  • Elisabeth Kochman

Communications

  • Adjunct Professor Sophie Scott OAM
  • Adjunct Associate Professor Jill Margo AM

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Mailing address
Level 5, Moore College
No.1 King Street Newtown
The University of Sydney, NSW, 2006