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Computational approaches to elucidate Multiple Sclerosis and Contact Dermatitis pathogenesis, and its treatment through ultraviolet light exposure

Allergies and autoimmunity are complex immune system aberrations. Both involve multiple immune cell populations coordinating across several organs of the body. The growing prevalenc more...

Supervisor(s): Read, Mark (Dr)

The role of key driver genes in the pathogenesis of acute renal allograft rejection

This is a PhD project. The successful applicant will be top up scholarship. This study will lead to publish high quality of papers and apply a new NHMRC project grant. more...

Supervisor(s): O'Connell, Philip (Professor), Hu, Min (Dr)

Utilising Clinically Relevant Mechanisms to Develop Neuroprotective Strategies in Glaucoma

Neuroprotective strategies for glaucoma therapy have been investigated extensively over the last few years with disappointing clinical trial results. However a significant proportio more...

Supervisor(s): White, Andrew (Dr)

Discovery and validation of new ceramide synthase inhibitors to treat metabolic disease

Ceramide synthase enzyme isoforms 1, 5, and 6, are heavily implicated as drivers of obesity, insulin resistance, and diabetes. Targeting these enzymes is expected to yield new thera more...

Supervisor(s): Don, Anthony (Associate Professor), Qi, Jacob (Dr)

Immune fitness as a measure of animal welfare

The Immune fitness as a measure of animal welfare study will examine several aspects in the identification of immune measures relevant to production outcome. This presents oppo more...

Supervisor(s): Purdie, Auriol (Dr)

Prevention of cardiac side effects of cancer treatment

This project will investigate a novel drug combination therapy that has potential benefits in cancer treatment induced heart failure by targeting Na+-K+ pump function. more...

Supervisor(s): Liu, Chia-chi (Dr), Ramussen, Helge (Professor)

The role of a novel mutant gene in dementia and motor neuron disease

We have identified a new gene that when mutated causes dementia and motor neuron disease (MND), diseases that are currently incurable. This project will examine how this mutated gen more...

Supervisor(s): Dobson-Stone, Carol (Dr)

Pharmacological targeting of sphingosine 1-phosphate receptors to promote remyelination in Alzheimer’s disease and multiple sclerosis

In this project you will investigate a new molecular pathway that is required for normal myelin formation, and the therapeutic potential of targeting this pathway to promote remyeli more...

Supervisor(s): Don, Anthony (Associate Professor)

Müller glial-neuronal-vascular interactions in retinal vascular diseases

Research projects in the Macular Research Group are focused on the cellular and molecular mechanisms of Müller glial-neuronal-vascular interactions in retinal diseases. The gro more...

Supervisor(s): Gillies, Mark (Professor), Shen, Weiyong (Dr)

Regulation of host resistance and immune response to human pathogens

The laboratory of Immunology and Host Defense focuses on the immune mechanisms that regulate host resistance to pathogens of global importance. It currently offers multiple projects more...

Supervisor(s): Feng, Carl (Dr)