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Genomic medicine for unravelling the challenges of pathogenesis and treatment of blindness due to childhood cataract and glaucoma

Novel disease genes and variants are identified that contribute to the blinding eye diseases of childhood cataract and glaucoma.  In this project further novel variants will be more...

Supervisor(s): Jamieson, Robyn (Associate Professor)

REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)

Pathways to therapies in blinding genetic retinal eye diseases

In this project, novel disease genes and variants are identified that cause blinding retinal eye diseases. Cellular, gene editing, proteomic and animal model approaches are taken to more...

Supervisor(s): Jamieson, Robyn (Associate Professor)

Mechanisms of brain development

The role of Ten_m proteins in brain development more...

Supervisor(s): Leamey, Catherine (Dr)

Stemming vision loss with stem cells

Studies to maximise recruitment of hematopoietic stem cells in various experimental models of retinopathy. more...

Supervisor(s): Chan-Ling, Tailoi (Professor)

Characterisation and application of human neural precursor cells in cell-based therapy

Applications of human fetal spinal-cord derived stem cells in cell-based therapy . . . more...

Supervisor(s): Chan-Ling, Tailoi (Professor)

The New Renin-Angiotensin System in the Human Eye

At present, the only treatment for glaucoma is intraocular pressure control. We know some people still get worse despite good pressure control. We have evidence that a system previo more...

Supervisor(s): White, Andrew (Dr)

Utilising Clinically Relevant Mechanisms to Develop Neuroprotective Strategies in Glaucoma

Neuroprotective strategies for glaucoma therapy have been investigated extensively over the last few years with disappointing clinical trial results. However a significant proportio more...

Supervisor(s): White, Andrew (Dr)

The Renin-Angiotensin System and its Role in Neuroprotective Strategies in a Glaucoma Model

At present, the only treatment for glaucoma is intraocular pressure control. We know some people still get worse despite good pressure control. We have evidence that a system previo more...

Supervisor(s): White, Andrew (Dr)

Early signs of diabetes complications in childhood onset diabetes mellitus

Early signs of diabetes complications in childhood onset diabetes will focus on newer methods to assess heart rate variation, peripheral nerve function, colour vision and vascular c more...

Supervisor(s): Donaghue, Kim (Professor)