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Exercise interventions for respiratory disease

We will investigate exercise testing and exercise interventions to improve the management of respiratory conditions such as chronic obstructive pulmonary disease (COPD) and cystic f more...

Supervisor(s): McKeough, Zoe (Associate Professor)

The molecular basis of persistence in clinical P. aeruginosa strains from cystic fibrosis patients

Pseudomonas aeruginosa, the leading cause of morbidity and mortality in people with cystic fibrosis (CF), adapts to survive in the CF lung through both mutation and gene expression more...

Supervisor(s): Manos, Jim (Dr), Triccas, Jamie (Dr)

Identification of proteins specific to transmissible Pseudomonas aeruginosa in cystic fibrosis infection

This project will characterize the molecular basis for increased infectivity caused by an epidemic strain of Pseudomonas aeruginosa (AES-1) which infects many patients treated in cy more...

Supervisor(s): Cordwell, Stuart (Professor)

Design and synthesis of selective anion receptors to facilitate transmembrane anion transport in epithelial cells

CF is a recessive genetic condition that results from the dysregulation of anion transport through the cystic fibrosis transmembrane regulator anion channel in epithelial cell membr more...

Supervisor(s): Gale, Philip (Professor)

Novel inhalation formulation to improve quality of life of cystic fibrosis sufferers

Respiratory infection is the number one cause of death world-wide with limited therapies other than tablet or intravenous injection. This multi-faceted PhD project will focus on dev more...

Supervisor(s): Traini, Daniela (Professor)

Investigation of virulence genes upregulated in coinfection between P. aeruginosa and other species

Identify the set of genes diffrentially expressed when P. aeruginosa is grown in coculture with three other infecting species. Select genes with virulence/persistence characteristic more...

Supervisor(s): Manos, Jim (Dr)

Cystic fibrosis related diabetes

To determine if a low glycaemic index diet improves control in CFRD and/or slows the progression of impaired glucose tolerance to CFRD more...

Supervisor(s): Steinbeck, Kate (Professor)