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Beyond Neuroinflammation: The Role of Microglia in Synaptic Plasticity

Microglia are the immune cells of the brain and are known to respond to infectious and non-infectious insults to the nervous system. Recently, a new function has been demonstrated f more...

Supervisor(s): Graeber, Manuel (Professor)

How do molecules make memories? Understanding synaptic plasticity at the level of protein pathways and signalling.

This project aims to discover and validate new molecular mechanisms of how synaptic plasticity, which underlies learning and memory, is regulated by protein interactions and phospho more...

Supervisor(s): Graham, Mark (Dr)

Investigating how endogenous opioid actions contribute to compulsive opioid use.

The widespread misuse of both prescribed and illicit opioids, termed the Opioid Crisis, has grave consequences for both individuals and our society. This project aims to understand more...

Supervisor(s): Bagley, Elena (Associate Professor)

Investigating how amygdala neural circuits contribute to opioid use disorders.

The widespread misuse of both prescribed and illicit opioids, termed the Opioid Crisis, has grave consequences for both individuals and our society. This project aims to understand more...

Supervisor(s): Bagley, Elena (Associate Professor)

Cellular mechanisms of opioid tolerance and dependence

Tolerance and dependence that contribute to opioid addiction will be studied using patch clamp analyses of cellular and synaptic electrophysiology in brain slices and behavioural co more...

Supervisor(s): Christie, Macdonald (Professor)

Investigating how we can utilize the endogenous opioid system to manage pain

The burden of chronic pain is a major cause of human suffering that is now estimated to cost Australia more than $73B per annum and even the most effective th¬¬erapeutics do more...

Supervisor(s): Bagley, Elena (Associate Professor)

PET imaging of glioma in a TSPO knockout model

Glioblastoma is the most frequent primary brain tumour and the most malignant glial neoplasm (glioma) with predominantly astrocytic differentiation. Due to their invasive nature, gl more...

Supervisor(s): Graeber, Manuel (Professor), Banati, Richard (Professor)