HSTO3004: Semester 2, 2021

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Units HSTO3004 Semester 2 2021 [Normal day]

Unit of study_

HSTO3004: Cells and Development: Practical (Adv)

Semester 2, 2021 [Normal day] - Remote

Overview

This advanced unit of study complements HSTO3003 (Cells and Development: Theory) and is catered to provide students with laboratory research experience leading to Honours and higher degrees. It will primarily cover the design and application of experimental procedures involved in cell and developmental biology, using appropriate molecular and cellular techniques to answer developmental questions raised in HSTO3003. This unit of study will promote hands on experience, allowing students to observe and examine developing and differentiating tissues at the macroscopic and microscopic level. The main emphasis of this unit of study will concentrate on practical approaches to understanding the mechanisms that control animal development. Some projects may examine early developmental processes such as fertilization, cleavage, gastrulation and the formation of the primary germ layers and tissues. The parts played by stem cells and inductive cell and tissue interactions in differentiation, morphogenesis and pattern formation can also be examined at cellular and molecular levels.

Unit details and rules

Unit code	HSTO3004
Academic unit	Department of Medical Sciences
Credit points	6
Prohibitions ?	None
Prerequisites ?	An annual average mark of 70 or above in the previous year and 72cp of 1000 to 3000 level units
Corequisites ?	None
Assumed knowledge ?	(ANAT2008 or BMED2401 or MEDS2005) and Human biology; BIOL1XX8 or BIOL1XX3 or MEDS1X01
Available to study abroad and exchange students	Yes

Teaching staff

Coordinator	Katie Dixon, katie.dixon@sydney.edu.au

Type	Description	Weight	Due	Length
Presentation	The language of development Upload photograph of class activity	5%	Week 03	3 hour class activity
Outcomes assessed:
Presentation	The Good Egg Image/report	5%	Week 04	2 pages
Outcomes assessed:
Assignment	Embryo ultrasonography Class activity, take-home quiz	5%	Week 04	3 hours
Outcomes assessed:
Assignment	Embryonic Stem Cell Differentiation Presentation slides and presentation	10%	Week 06	10 minutes
Outcomes assessed:
Assignment	Human skeletal development Poster	15%	Week 08	Poster presentation - 10 mins
Outcomes assessed:
Assignment	Modelling embryonic pathogenesis Report and clay model	15%	Week 08	Written task and clay models
Outcomes assessed:
Presentation	Skin Deep / Cell Migration Presentation	25%	Week 10	20 minutes
Outcomes assessed:
Presentation	Epithelial to mesenchymal transition Presentation	20%	Week 13	15 minutes
Outcomes assessed:

Assessment summary

Detailed information for each assessment can be found on Canvas.

Assessment criteria

The University awards common result grades, set out in the Coursework Policy 2014 (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

Result name	Mark range	Description
High distinction	85 - 100
Distinction	75 - 84
Credit	65 - 74
Pass	50 - 64
Fail	0 - 49	When you don’t meet the learning outcomes of the unit to a satisfactory standard.

For more information see sydney.edu.au/students/guide-to-grades.

For more information see guide to grades.

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

Deduction of 5% of the maximum mark for each calendar day after the due date.
After ten calendar days late, a mark of zero will be awarded.

Academic integrity

The Current Student website provides information on academic integrity and the resources available to all students. The University expects students and staff to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.

We use similarity detection software to detect potential instances of plagiarism or other forms of academic integrity breach. If such matches indicate evidence of plagiarism or other forms of academic integrity breaches, your teacher is required to report your work for further investigation.

You may only use artificial intelligence and writing assistance tools in assessment tasks if you are permitted to by your unit coordinator, and if you do use them, you must also acknowledge this in your work, either in a footnote or an acknowledgement section.

Studiosity is permitted for postgraduate units unless otherwise indicated by the unit coordinator. The use of this service must be acknowledged in your submission.

Learning support

Simple extensions

If you encounter a problem submitting your work on time, you may be able to apply for an extension of five calendar days through a simple extension.  The application process will be different depending on the type of assessment and extensions cannot be granted for some assessment types like exams.

Special consideration

If exceptional circumstances mean you can’t complete an assessment, you need consideration for a longer period of time, or if you have essential commitments which impact your performance in an assessment, you may be eligible for special consideration or special arrangements.

Special consideration applications will not be affected by a simple extension application.

Using AI responsibly

Co-created with students, AI in Education includes lots of helpful examples of how students use generative AI tools to support their learning. It explains how generative AI works, the different tools available and how to use them responsibly and productively.

Weekly schedule

WK	Topic	Learning activity
Week 01	Introduction and Science Communication	Lecture (3 hr)
Week 01	Embryonic stem cell differentiation - 1	Tutorial (3 hr)
Week 02	The Good Egg	Practical (3 hr)
Week 02	Embryo Ulstrasonography	Practical (3 hr)
Week 03	The Language of Development	Workshop (3 hr)
Week 03	Embryonic stem cell differentiation - 2	Practical (3 hr)
Week 04	Skin Deep - 1	Practical (3 hr)
Week 04	Skin Deep - 2	Practical (3 hr)
Week 05	Skin Deep - 3	Practical (3 hr)
Week 05	Modelling Embryonic Pathology - 1	Practical (3 hr)
Week 06	Embryonic stem cell differentiation - 3	Practical (3 hr)
Week 06	Skeletal development - 1	Practical (3 hr)
Week 07	Modelling Embryonic Pathology - 2	Practical (3 hr)
Week 08	FAS - the great debate	Practical (3 hr)
Week 08	Skeletal development posters	Presentation (3 hr)
Week 09	Cell migration: the amazing race - 1	Practical (3 hr)
Week 09	Cell migration: the amazing race - 2	Practical (3 hr)
Week 10	Cell migration: the amazing race - 3	Practical (3 hr)
Week 10	Cell migration presentations	Presentation (3 hr)
Week 11	Cancer biology: epithelial to mesenchymal transition - 1	Practical (3 hr)
Week 11	Cancer biology: epithelial to mesenchymal transition - 2	Practical (3 hr)
Week 12	Cancer biology: epithelial to mesenchymal transition - 3	Practical (3 hr)
Week 13	Cancer biology: epithelial to mesenchymal transition - presentations	Presentation (3 hr)

Attendance and class requirements

Attendance: All students are expected to attend all lectures, practical classes, tutorials, and case studies. A variety of notes, handouts, data sheets, and information provided throughout the Unit of Study are intended to supplement the lectures not to substitute for them. Absences from all scheduled practical sessions, tutorials and case studies must be explained and supported by appropriate documentation.

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Learning outcomes

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University's graduate qualities and are assessed as part of the curriculum.

Outcomes
Graduate qualities

At the completion of this unit, you should be able to:

LO1. Develop the skills required to independently design an experiment in the field of developmental or cell biology. This includes developing knowledge regarding appropriate controls, repeats and some aspects of statistical analysis.
LO2. Master important concepts in developmental and cell biology by engaging in hands-on activities within these fields.
LO3. Develop an understanding of ethical considerations regarding museums with human samples and practical activities involving cadaveric animal material.
LO4. Master presentation skills and an understanding of the scientific language used in these fields.

Graduate qualities

The graduate qualities are the qualities and skills that all University of Sydney graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1	Depth of disciplinary expertise Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.
GQ2	Critical thinking and problem solving Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.
GQ3	Oral and written communication Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.
GQ4	Information and digital literacy Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.
GQ5	Inventiveness Generating novel ideas and solutions.
GQ6	Cultural competence Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.
GQ7	Interdisciplinary effectiveness Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.
GQ8	Integrated professional, ethical, and personal identity An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.
GQ9	Influence Engaging others in a process, idea or vision.

Outcome map

Learning outcomes	Graduate qualities
Learning outcomes

Responding to student feedback

This section outlines changes made to this unit following staff and student reviews.

No changes were made based on positive feedback. Changes have been made to introduce a new topic.

Additional information

Work, health and safety

As a new facility, the CPC is encouraging best practices in education and research. This includes best practices in Work, Health and Safety (WHS). These practices are designed with your personal safety in mind. To this end, you are required to complete a set of inductions. These are not complicated and do not take large periods of time to complete. However, you will need to complete these before you can engage in research in the CPC PC2 laboratory space. Please complete the induction programmes that will be linked to Canvas. To demonstrate your completion please print the last page of each programme, sign and date the page and give this to Dr. Stuart Fraser before entering the CPC PC2 laboratory space. This will confirm that you have completed the induction processes. Also note that enclosed, non-permeable shoes are required for working in the PC2 lab. Again, this is for your protection. A pdf has been uploaded to the Canvas site indicating appropriate and inappropriate shoes. If you arrive at the PC2 lab in inappropriate foot ware you will be refused entry.

Disclaimer

The University reserves the right to amend units of study or no longer offer certain units, including where there are low enrolment numbers.

To help you understand common terms that we use at the University, we offer an online glossary.

Current students

Overview

Overview

Unit details and rules

Teaching staff

Assessment

Assessment

Assessment summary

Assessment criteria

Late submission

Academic integrity

Learning support

Learning support

Simple extensions

Special consideration

Using AI responsibly

Weekly schedule

Weekly schedule

Attendance and class requirements

Study commitment

Learning outcomes

Learning outcomes

Graduate qualities

Outcome map

Responding to student feedback

Responding to student feedback

Additional information

Additional information

Work, health and safety

Disclaimer

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