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Unit of study_

PHAR1822: Physical Pharmaceutics and Formulation A

Semester 2, 2020 [Normal day] - Camperdown/Darlington, Sydney

This unit of study aims to facilitate an understanding of the basic scientific concepts behind designing and using liquid or semi-solid pharmaceutical dosage forms to deliver a drug. Carrying on from PHAR1812 where different dose forms and the importance of the route of administration was introduced, this unit looks at topics such as diffusion and dissolution of drugs, drug solubilisation, crystal polymorphism, suspension and emulsion-based dosage forms. With a grounding in these concepts the unit then goes on to explore specific methods of drug delivery, including: auricular, ocular, intranasal, lung, and intravenous and intramuscular injections, including hospital practice points for pharmacists. This unit of study also includes mathematical tools required for other units of study.

Unit details and rules

Unit code PHAR1822
Academic unit Pharmacy
Credit points 6
Prohibitions
? 
None
Prerequisites
? 
None
Corequisites
? 
None
Assumed knowledge
? 

HSC Chemistry

Available to study abroad and exchange students

Yes

Teaching staff

Coordinator Nial Wheate, nial.wheate@sydney.edu.au
Type Description Weight Due Length
Final exam (Record+) Type B final exam hurdle task Final exam
(60% MCQ, 40% short answer questions) for this Exam.
50% Formal exam period 1.5 hours
Outcomes assessed: LO1 LO2 LO4
Participation Laboratories
Participation
15% Multiple weeks n/a
Outcomes assessed: LO1 LO2 LO4 LO5
Assignment group assignment Explainer guide for patients
Development of an explainer guide to patients
20% STUVAC
Due date: 27 Nov 2020 at 17:00
Two A4 sizes pages
Outcomes assessed: LO4 LO5 LO6
Tutorial quiz Maths quiz
Short answer questions
15% Week 06 1 hour
Outcomes assessed: LO3
hurdle task = hurdle task ?
group assignment = group assignment ?
Type B final exam = Type B final exam ?

Assessment summary

  • Maths quiz: Students will complete an in-class written test which will take place during a scheduled maths tutorial class. The test will consist of 15 questions.
  • Laboratories: Students will be awarded three marks per laboratory if the tutor deems participation satisfactory for the class. Students will receive no marks if the laboratory tutor deems their participation to be unsatisfactory. 
  • Explainer guide for patients: Students are required to produce a two page brochure for hospital patients that explain what’s in their IV bags and how they work. As this is a group assessment, Sparkplus will be used for peer assessment on the task.Peer assessment (relative performance factor) will be applied to moderate the groupwork marks. Peer assessment will be completed online using Sparkplus to obtain a factor between 0-1
  • Final exam: The final exam comprises of multiple choice and short answer questions.  Students must pass this assessment task to satisfy the requirements for this unit. Failure to complete this assessment item will result in students being awarded a maximum of 45 F, regardless of cumulative marks obtained in the unit of study. If you wish to sit your Exam on Campus, a limited number of on campus places will be available through an online booking system. Replacement Exam for this UoS will be held in the formal Replacement Exam Period (i.e. 11/01/2021 to 14/01/2021).

Detailed information for each assessment can be found on Canvas.

Assessment criteria

The University awards common result grades, set out in the Coursework Policy 2014 (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

Result name

Mark range

Description

High distinction

85 - 100

 

Distinction

75 - 84

 

Credit

65 - 74

 

Pass

50 - 64

 

Fail

0 - 49

When you don’t meet the learning outcomes of the unit to a satisfactory standard.

For more information see sydney.edu.au/students/guide-to-grades.

For more information see guide to grades.

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

  • Deduction of 5% of the maximum mark for each calendar day after the due date.
  • After ten calendar days late, a mark of zero will be awarded.

This unit has an exception to the standard University policy or supplementary information has been provided by the unit coordinator. This information is displayed below:

Non submission of peer assessment will result in a factor of zero (0) being applied to the non-submitter’s groupwork mark.

Academic integrity

The Current Student website  provides information on academic integrity and the resources available to all students. The University expects students and staff to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.  

We use similarity detection software to detect potential instances of plagiarism or other forms of academic integrity breach. If such matches indicate evidence of plagiarism or other forms of academic integrity breaches, your teacher is required to report your work for further investigation.

You may only use artificial intelligence and writing assistance tools in assessment tasks if you are permitted to by your unit coordinator, and if you do use them, you must also acknowledge this in your work, either in a footnote or an acknowledgement section.

Studiosity is permitted for postgraduate units unless otherwise indicated by the unit coordinator. The use of this service must be acknowledged in your submission.

Simple extensions

If you encounter a problem submitting your work on time, you may be able to apply for an extension of five calendar days through a simple extension.  The application process will be different depending on the type of assessment and extensions cannot be granted for some assessment types like exams.

Special consideration

If exceptional circumstances mean you can’t complete an assessment, you need consideration for a longer period of time, or if you have essential commitments which impact your performance in an assessment, you may be eligible for special consideration or special arrangements.

Special consideration applications will not be affected by a simple extension application.

Using AI responsibly

Co-created with students, AI in Education includes lots of helpful examples of how students use generative AI tools to support their learning. It explains how generative AI works, the different tools available and how to use them responsibly and productively.

WK Topic Learning activity Learning outcomes
Multiple weeks Maths Lecture (1 hr) LO3
Advil liquid capsule testing Science laboratory (3 hr) LO1 LO2 LO5
Paracetamol elixirs Science laboratory (3 hr) LO1 LO2 LO5
Micelles Science laboratory (3 hr) LO1 LO2 LO5
Emulsions Science laboratory (3 hr) LO1 LO2 LO5
Paste compounding and testing Science laboratory (3 hr) LO1 LO2 LO5
Week 05 Liquids and solutions Lecture (1 hr)  
Rheology Lecture (1 hr)  
Week 06 Osmosis Lecture (1 hr)  
Briefing on group assigment Lecture (1 hr)  
Week 07 Emulsions Lecture (1 hr)  
Freezing point depression Lecture (1 hr)  
Week 08 Suspensions Lecture (1 hr)  
Complementary medicines Lecture (1 hr)  
Week 09 Liquid formulation Lecture (1 hr)  
Week 10 Proteins and aerosols Lecture (1 hr)  
Week 11 Injectables Lecture (1 hr)  
Body systems Lecture (1 hr)  
Formulation of medicinal cannabis Lecture (1 hr) LO2 LO4
Week 12 Past exams Lecture (1 hr)  

Attendance and class requirements

  • Attendance: Students must attend the scheduled laboratory classes. Failure to turn up on time, or if the student goes to the wrong laboratory class, will result in a mark of zero for that laboratory class. On-time attendance for labs is defined as arrival for the lab session no later than 10 minutes past the hour. A student who arrives after 10 minutes or later past the hour will be deemed unsatisfactory and will not be permitted entry that day.
  • Required materials: Students will need to bring a device (laptop, tablet or phone) to laboratory classes. If the student cannot bring a device, Faculty devices will be available. 

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Required readings

Recommended reading: Aulton's Pharmaceutics: The Design and Manufacture of Medicines, Churchill Livingstone Elsevier.

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University's graduate qualities and are assessed as part of the curriculum.

At the completion of this unit, you should be able to:

  • LO1. Undertake complex, multistep pharmaceutical calculations
  • LO2. Understand the forces, science and terminology behind liquid and semi-solid dosage forms
  • LO3. Understand and apply the mathematical concept of calculus to pharmacy
  • LO4. Understand and explain to others the different types of parenteral dosage forms, their medical uses, reasons for selection and how they are prepared.
  • LO5. Develop skills in teamwork and leadership in pharmaceutical science
  • LO6. Develop written communication skills

Graduate qualities

The graduate qualities are the qualities and skills that all University of Sydney graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1 Depth of disciplinary expertise

Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.

GQ2 Critical thinking and problem solving

Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.

GQ3 Oral and written communication

Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.

GQ4 Information and digital literacy

Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.

GQ5 Inventiveness

Generating novel ideas and solutions.

GQ6 Cultural competence

Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.

GQ7 Interdisciplinary effectiveness

Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.

GQ8 Integrated professional, ethical, and personal identity

An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.

GQ9 Influence

Engaging others in a process, idea or vision.

Outcome map

Learning outcomes Graduate qualities
GQ1 GQ2 GQ3 GQ4 GQ5 GQ6 GQ7 GQ8 GQ9

Alignment with Competency standards

Outcomes Competency standards
LO1
Performance Outcomes Framework - Australian Pharmacy Council - At the point of general registration as a pharmacist - APC
5.1. acting as a role model, facilitator and/or mentor to students, colleagues, other pharmacy team members and other health care professionals
Performance Outcomes Framework - Australian Pharmacy Council - On successful completion of an approved pharmacy degree program - APC
1.4.a. demonstrating contemporary knowledge and application of legal requirements relating to community and hospital pharmacy practice within their jurisdiction
LO2
Performance Outcomes Framework - Australian Pharmacy Council - At the point of general registration as a pharmacist - APC
5.1. acting as a role model, facilitator and/or mentor to students, colleagues, other pharmacy team members and other health care professionals
Performance Outcomes Framework - Australian Pharmacy Council - On successful completion of an approved pharmacy degree program - APC
1.4.a. demonstrating contemporary knowledge and application of legal requirements relating to community and hospital pharmacy practice within their jurisdiction
LO3
Performance Outcomes Framework - Australian Pharmacy Council - At the point of general registration as a pharmacist - APC
5.1. acting as a role model, facilitator and/or mentor to students, colleagues, other pharmacy team members and other health care professionals
Performance Outcomes Framework - Australian Pharmacy Council - On successful completion of an approved pharmacy degree program - APC
1.4.a. demonstrating contemporary knowledge and application of legal requirements relating to community and hospital pharmacy practice within their jurisdiction
LO4
Performance Outcomes Framework - Australian Pharmacy Council - At the point of general registration as a pharmacist - APC
5.1. acting as a role model, facilitator and/or mentor to students, colleagues, other pharmacy team members and other health care professionals
Performance Outcomes Framework - Australian Pharmacy Council - On successful completion of an approved pharmacy degree program - APC
1.4.a. demonstrating contemporary knowledge and application of legal requirements relating to community and hospital pharmacy practice within their jurisdiction
LO5
Performance Outcomes Framework - Australian Pharmacy Council - At the point of general registration as a pharmacist - APC
5.1. acting as a role model, facilitator and/or mentor to students, colleagues, other pharmacy team members and other health care professionals
Performance Outcomes Framework - Australian Pharmacy Council - On successful completion of an approved pharmacy degree program - APC
1.4.a. demonstrating contemporary knowledge and application of legal requirements relating to community and hospital pharmacy practice within their jurisdiction
LO6
Performance Outcomes Framework - Australian Pharmacy Council - At the point of general registration as a pharmacist - APC
5.1. acting as a role model, facilitator and/or mentor to students, colleagues, other pharmacy team members and other health care professionals
Performance Outcomes Framework - Australian Pharmacy Council - On successful completion of an approved pharmacy degree program - APC
1.4.a. demonstrating contemporary knowledge and application of legal requirements relating to community and hospital pharmacy practice within their jurisdiction

This section outlines changes made to this unit following staff and student reviews.

Feedback from the students has always been positive for this unit of study. The students don't see the value of the maths lectures, and I agree, but I have not been given permission to remove it from the unit.

Teacher consultation guidelines: Meetings available at any time. No appointment necessary.

Additional costs

Nil

Work, health and safety

Students must wear laboratory coat and safety glasses in all laboratory classes.

Disclaimer

The University reserves the right to amend units of study or no longer offer certain units, including where there are low enrolment numbers.

To help you understand common terms that we use at the University, we offer an online glossary.