Outline

Overview

This unit of study builds on the material presented in Physical Pharmaceutics and Formulation A. The topics covered in this unit include: solid dose forms and particle science; dispersion dose forms including suspensions, colloidal dispersions, and emulsions; topical dose forms and semisolids; inhalation pharmaceutical aerosols; protein and peptide drugs and formulations; rectal products and novel drug delivery technologies; biomaterials; and material characterisation techniques. Aspects pertaining to the stability of dose forms are also presented in this unit. Practical activities relate to the preparation, quality control and quality assurance of a marketed solid (tablet) dosage form.

Unit details and rules

Academic unit	Pharmacy
Credit points	6
Prerequisites ?	(CHEM1611 or CHEM11X1 or CHEM19X1 or CHEM1903 or CHEM1612 or CHEM11X2 or CHEM19X2 or CHEM1904) and PHAR1812 and PHAR1822.
Corequisites ?	None
Prohibitions ?	None
Assumed knowledge ?	None
Available to study abroad and exchange students	Yes

Teaching staff

Coordinator	Wojciech Chrzanowski, wojciech.chrzanowski@sydney.edu.au
Lecturer(s)	Philip Kwok, philip.kwok@sydney.edu.au
Lecturer(s)	Kim Chan, kim.chan@sydney.edu.au
Tutor(s)	Shiva Divakarla, kamini.divakarla@sydney.edu.au
	Qingyu Lei, qingyu.lei@sydney.edu.au
	Thanh Phan, thanh.phan@sydney.edu.au
	Ramya Varanasi, ramya.varanasi@sydney.edu.au

Type	Description	Weight	Due	Length
Final exam (Record+)	Final examination MCQ and short answer (MCQ 63.5% & SAQ 36.5% of the total exam mark)	65%	Formal exam period	2 hours
Outcomes assessed:
Online task	Online quizzes 3 x MCQ quizzes	5%	Multiple weeks	5 min
Outcomes assessed:
Assignment	Laboratory pre-work quiz - Practical 1a MCQ	3%	Multiple weeks	5 min
Outcomes assessed:
Assignment	Practical 1b Report	20%	Multiple weeks	Prepared during the class (2x4h)
Outcomes assessed:
Participation	Practical Participation	2%	Ongoing	n/a
Outcomes assessed:
Online task	Mid-semester quiz MCQ	5%	Week 09	1 hour
Outcomes assessed:
= hurdle task ? = group assignment ? = Type B final exam ?

Assessment summary

Laboratory practicals: The practical exercises will be performed in small groups during the scheduled practical sessions. The objective of the practical exercises is to assess individual’s and group’s abilities to understand the underlying principles of the course through experimental investigation and critical analysis. Students must obtain a grade of ‘Pass’ in this assessment to satisfy the requirements for this unit of study. If this assessment is not passed, the maximum final grade possible to obtain will be 45 F, regardless of the total raw mark obtained for the unit of study.
Mid-semester quiz: The mid semester quiz will consist of multiple choice questions.
Online quizzes: The online quizzes will consist of three separate online quizzes that consist of three multiple-choice questions.
Final examination: The final examination will consist of multiple choice questions and short answer questions. Students must obtain a grade of ‘Pass’ in this assessment to satisfy the requirements for this unit of study. If this assessment is not passed, the maximum final grade possible to obtain will be 45 F, regardless of the total raw mark obtained for the unit of study. If you wish to sit your exam on-campus, a limited number of on-campus places will be available through an online booking system.
The replacement exam will be held in the formal Replacement Exam period (11/01/2021 to 14/01/2021).

Detailed information for each assessment can be found on Canvas.

Assessment criteria

The University awards common result grades, set out in the Coursework Policy 2014 (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

Result name	Mark range	Description
High distinction	85 - 100
Distinction	75 - 84
Credit	65 - 74
Pass	50 - 64
Fail	0 - 49	When you don’t meet the learning outcomes of the unit to a satisfactory standard.

For more information see guide to grades.

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

Deduction of 5% of the maximum mark for each calendar day after the due date.
After ten calendar days late, a mark of zero will be awarded.

Academic integrity

The Current Student website provides information on academic integrity and the resources available to all students. The University expects students and staff to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.

We use similarity detection software to detect potential instances of plagiarism or other forms of academic integrity breach. If such matches indicate evidence of plagiarism or other forms of academic integrity breaches, your teacher is required to report your work for further investigation.

Use of generative artificial intelligence (AI) and automated writing tools

You may only use generative AI and automated writing tools in assessment tasks if you are permitted to by your unit coordinator. If you do use these tools, you must acknowledge this in your work, either in a footnote or an acknowledgement section. The assessment instructions or unit outline will give guidance of the types of tools that are permitted and how the tools should be used.

Your final submitted work must be your own, original work. You must acknowledge any use of generative AI tools that have been used in the assessment, and any material that forms part of your submission must be appropriately referenced. For guidance on how to acknowledge the use of AI, please refer to the AI in Education Canvas site.

The unapproved use of these tools or unacknowledged use will be considered a breach of the Academic Integrity Policy and penalties may apply.

Studiosity is permitted unless otherwise indicated by the unit coordinator. The use of this service must be acknowledged in your submission as detailed on the Learning Hub’s Canvas page.

Outside assessment tasks, generative AI tools may be used to support your learning. The AI in Education Canvas site contains a number of productive ways that students are using AI to improve their learning.

Learning support

Simple extensions

If you encounter a problem submitting your work on time, you may be able to apply for an extension of five calendar days through a simple extension.  The application process will be different depending on the type of assessment and extensions cannot be granted for some assessment types like exams.

Special consideration

If exceptional circumstances mean you can’t complete an assessment, you need consideration for a longer period of time, or if you have essential commitments which impact your performance in an assessment, you may be eligible for special consideration or special arrangements.

Special consideration applications will not be affected by a simple extension application.

Using AI responsibly

Co-created with students, AI in Education includes lots of helpful examples of how students use generative AI tools to support their learning. It explains how generative AI works, the different tools available and how to use them responsibly and productively.

Weekly schedule

WK	Topic	Learning activity
-	Protein formulations	Lecture and tutorial (2 hr)
Multiple weeks	Characterisation of particulate systems	Lecture and tutorial (3 hr)
	Solid oral dosage forms: tablets	Lecture and tutorial (6 hr)
	Capsule technology	Lecture and tutorial (3 hr)
	Solids advanced	Lecture and tutorial (4 hr)
	Inhalation aerosols	Lecture and tutorial (5 hr)
	Solids - Aerosols	Lecture and tutorial (3 hr)
	Manufacturing, characterization and quality control of tablet	Science laboratory (8 hr)
Week 05	Introduction to the stability of pharmaceutical dose forms	Lecture and tutorial (1 hr)

Attendance and class requirements

Attendance: In regards to practical classes, both practical class sessions must be attended. A roll will be taken.
Required materials: Email and Internet access is strongly recommended. Students will be required to access materials online via Canvas. While working within the dispensing laboratory, all students must wear a clean white lab coat and wear shoes which completely cover the feet (no sandals or thongs are permitted). When preparing products or working with ingredients, all students must wear rubber gloves (supplied in the laboratory) and safety glasses which meet the requirements as displayed in the notice boards in the laboratory.

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Required readings

All readings for this unit can be accessed through the Library eReserve, available on Canvas.

Aulton M.E. Pharmaceutics: The Science of Dosage Form Design (7th edn) Churchill Livingston

Learning outcomes

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University's graduate qualities and are assessed as part of the curriculum.

Outcomes
Graduate qualities

At the completion of this unit, you should be able to:

LO1. understand principles involved in the formulation of medicaments that are composed of materials in the solid state
LO2. understand the physicochemical principles that underlie materials in the solid form
LO3. calculate the amounts of ingredients required in a formulation
LO4. discuss the manufacturing procedures and quality control procedures for these products
LO5. understand the design and formulation of novel drug delivery systems.
LO6. design methodology for quality control of pharmaceutical products.

Graduate qualities

The graduate qualities are the qualities and skills that all University of Sydney graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1	Depth of disciplinary expertise Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.
GQ2	Critical thinking and problem solving Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.
GQ3	Oral and written communication Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.
GQ4	Information and digital literacy Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.
GQ5	Inventiveness Generating novel ideas and solutions.
GQ6	Cultural competence Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.
GQ7	Interdisciplinary effectiveness Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.
GQ8	Integrated professional, ethical, and personal identity An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.
GQ9	Influence Engaging others in a process, idea or vision.

Outcome map

Learning outcomes	Graduate qualities
Learning outcomes

Responding to student feedback

This section outlines changes made to this unit following staff and student reviews.

Exam review sessions. Integration of the post-laboratory quiz with the report.

Additional information

Work, health and safety

While working within the laboratory, all students must wear a clean white lab coat and wear shoes which completely cover the feet (no sandals or thongs are permitted).

Disclaimer

Important: the University of Sydney regularly reviews units of study and reserves the right to change the units of study available annually. To stay up to date on available study options, including unit of study details and availability, refer to the relevant handbook.

To help you understand common terms that we use at the University, we offer an online glossary.

Current students

Overview

Overview

Unit details and rules

Teaching staff

Assessment

Assessment

Assessment summary

Assessment criteria

Late submission

Academic integrity

Learning support

Learning support

Simple extensions

Special consideration

Using AI responsibly

Weekly schedule

Weekly schedule

Attendance and class requirements

Study commitment

Required readings

Learning outcomes

Learning outcomes

Graduate qualities

Outcome map

Responding to student feedback

Responding to student feedback

Additional information

Additional information

Work, health and safety

Disclaimer

On this page

Useful links

PHAR2823: Physical Pharmaceutics and Formulation B

Semester 2, 2020 [Normal day] - Camperdown/Darlington, Sydney

Overview

Overview

Unit details and rules

Teaching staff

Assessment

Assessment

Assessment summary

Assessment criteria

Late submission

Academic integrity

Learning support

Learning support

Simple extensions

Special consideration

Using AI responsibly

Weekly schedule

Weekly schedule

Attendance and class requirements

Study commitment

Required readings

Learning outcomes

Learning outcomes

Graduate qualities

Outcome map

Responding to student feedback

Responding to student feedback

Additional information

Additional information

Work, health and safety

Disclaimer

On this page

Useful links