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Unit of study_

PHSI3912: Frontiers in Physiology (Advanced)

The aim of this unit is to highlight the latest advances that underpin our understanding of human physiology. PHSI3912 contains modules that focus on selective topics. Each topic will be explored indepth and students will get a comprehensive view of the research that is driving the frontiers of our knowledge and revealing the fundamental mechanisms that lead to human disease.

Details

Academic unit Department of Medical Sciences
Unit code PHSI3912
Unit name Frontiers in Physiology (Advanced)
Session, year
? 
Semester 2, 2022
Attendance mode Normal day
Location Remote
Credit points 6

Enrolment rules

Prohibitions
? 
PHSI3012 or PHSI3007 or PHSI3907 or PHSI3008 or PHSI3908
Prerequisites
? 
A mark of 70 or above in [(PHSI2X05 and PHSI2X06) or (PHSI2X07 or MEDS2001) or 12 cp from (BMED2402 or BMED2403 or BMED2404 or BMED2406)]
Corequisites
? 
None
Available to study abroad and exchange students

No

Teaching staff and contact details

Coordinator Melissa Cameron, melissa.cameron@sydney.edu.au
Type Description Weight Due Length
Assignment Reseach analysis
Submitted work
20% Formal exam period 1 week
Outcomes assessed: LO1 LO2 LO3 LO4 LO5 LO7 LO8
Small test Module 1 test
MCQ and SAQ
10% Week 05 40 min
Outcomes assessed: LO1 LO4 LO3 LO2
Assignment Cancer practical report
Report
10% Week 07
Due date: 18 Sep 2022 at 23:59
1500 words
Outcomes assessed: LO1 LO2 LO3 LO4 LO5 LO6 LO7 LO8 LO9 LO10
Small test Module 2 test
MCQ and SAQ
10% Week 09 40 min
Outcomes assessed: LO1 LO4 LO3 LO2
Assignment Precision medicine report
Brochure
20% Week 12
Due date: 30 Oct 2022 at 23:59
2000 words
Outcomes assessed: LO1 LO5 LO6 LO7 LO8 LO10 LO11
Small test Module 3 test
MCQ and SAQ
10% Week 13 40 min
Outcomes assessed: LO1 LO4 LO3 LO2
Presentation group assignment Project presentation
Project presentation
20% Week 13 15 min
Outcomes assessed: LO1 LO2 LO3 LO4 LO5 LO6 LO7 LO8 LO9 LO10
Group assignment with individually assessed component = group assignment with individually assessed component ?

Detailed information for each assessment can be found on Canvas.

Assessment criteria

The University awards common result grades, set out in the Coursework Policy 2014 (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

Result name

Mark range

Description

High distinction

85 - 100

To be awarded to students who, in their performance in assessment tasks, demonstrate the learning outcomes for the unit at an exceptional standard as defined by grade descriptors or exemplars established by the faculty.

Distinction

75 - 84

To be awarded to students who, in their performance in assessment tasks, demonstrate the learning outcomes for the unit at a very high standard as defined by grade descriptors or exemplars established by the faculty.

Credit

65 - 74

To be awarded to students who, in their performance in assessment tasks, demonstrate the learning outcomes for the unit at a good standard as defined by grade descriptors or exemplars established by the faculty.

Pass

50 - 64

To be awarded to students who, in their performance in assessment tasks, demonstrate the learning outcomes for the unit at an acceptable standard as defined by grade descriptors or exemplars established by the faculty.

Fail

0 - 49

To be awarded to students who, in their performance in assessment tasks, fail to demonstrate the learning outcomes for the unit at an acceptable standard established by the faculty. This grade, with corresponding mark, should also be used in cases where a student fails to achieve a mandated standard in a compulsory assessment, thereby failing to demonstrate the learning outcomes to a satisfactory standard. In such cases the student will receive the mark awarded by the faculty up to a maximum of 49.

For more information see sydney.edu.au/students/guide-to-grades.

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

  • Deduction of 5% of the maximum mark for each calendar day after the due date.
  • After ten calendar days late, a mark of zero will be awarded.

Special consideration

If you experience short-term circumstances beyond your control, such as illness, injury or misadventure or if you have essential commitments which impact your preparation or performance in an assessment, you may be eligible for special consideration or special arrangements.

Academic integrity

The Current Student website provides information on academic integrity and the resources available to all students. The University expects students and staff to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.

We use similarity detection software to detect potential instances of plagiarism or other forms of academic integrity breach. If such matches indicate evidence of plagiarism or other forms of academic integrity breaches, your teacher is required to report your work for further investigation.

You may only use artificial intelligence and writing assistance tools in assessment tasks if you are permitted to by your unit coordinator, and if you do use them, you must also acknowledge this in your work, either in a footnote or an acknowledgement section.

Studiosity is permitted for postgraduate units unless otherwise indicated by the unit coordinator. The use of this service must be acknowledged in your submission.

WK Topic Learning activity Learning outcomes
Week 01 Cancer overview Lecture (1 hr) LO1 LO2
Experimental modelling of cancer Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Week 02 Drivers of cancer phenotype Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Cancer cell interactions Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Week 03 Metastasis Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Cancer therapeutics Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Week 04 Future directions in cancer Lecture (4 hr) LO1 LO2 LO3 LO7
Module 1 review Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Week 05 Obesity and its related disorders Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Obesity complications 1: Lipid disorders and dyslipidaemia Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Cancer practical Practical (2 hr) LO1 LO5 LO6 LO7 LO8 LO9 LO10 LO11
Week 06 Obesity complications 2: Insulin resistance and Type 2 diabetes Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Type 1 and Type 2 diabetes complications Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Week 07 Obesity/Type 2 diabetes and cancer Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Treatments 1: Diet and Exercise Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Week 08 Treatments 2: Drugs and Surgery Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Module 2 review Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Week 09 Personalised medicine versus other Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Central dogma - coding versus non-coding Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Project workshop 1 Workshop (3 hr) LO1 LO4 LO5 LO6 LO7 LO8 LO9 LO10
Week 10 Technologies in personalised medicine Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Detection-based assays Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Precision medicine activity Workshop (3 hr) LO1 LO5 LO6 LO7 LO8 LO9 LO10 LO11
Week 11 TBC Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
TBC Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Project workshop 2 Workshop (3 hr) LO1 LO4 LO5 LO6 LO7 LO8 LO9 LO10
Week 12 TBC Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
TBC Lecture (1 hr) LO1 LO2 LO3 LO4 LO7
Week 13 Project presentations Presentation (3 hr) LO1 LO4 LO5 LO6 LO7 LO8 LO9 LO10

Attendance and class requirements

Attendance: All students enrolled in PHSI3012 or PHSI3912 are to attend and engage in all classes, including lectures. Attendance is compulsory to all PBLs and practicals and attendance will be taken. Failure to attend without the granting of special consideration may lead to the awarding of an absent fail (AF) grade. 

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Required readings

All readings for this unit can be accessed through  Canvas.

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University’s graduate qualities and are assessed as part of the curriculum.

At the completion of this unit, you should be able to:

  • LO1. describe the physiological systems that maintain normal tissue function and have implications for the physiology of the body during disease
  • LO2. provide examples explaining how genetic and other abnormalities can alter the normal physiology of such systems
  • LO3. explain how mutations in genes important in regulating elements of whole-body physiology result in specific symptoms of diseases
  • LO4. apply your understanding of normal cellular and molecular function to explain current treatments for disease
  • LO5. search for information from scientific journals, synthesise data and use the knowledge obtained to answer specific questions in cellular physiology and pathophysiology of human diseases that you are studying
  • LO6. work as part of a team to plan and organise scientific experiments and confidently communicate your scientific findings
  • LO7. understand the principles underlying commonly used experimental methods in whole-body physiology
  • LO8. synthesise relevant findings from original research articles
  • LO9. work cooperatively in organising and sharing intellectual tasks with your group members to construct and present a coherent talk or presentation that explains the current findings in a given research field
  • LO10. design and interpret cellular biological experiments to investigate a problem
  • LO11. design and apply electrophysiological analysis to a living tissue preparation and interpreting and presenting your own experimental results in terms of the underlying theory.

Graduate qualities

The graduate qualities are the qualities and skills that all University of Sydney graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1 Depth of disciplinary expertise

Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.

GQ2 Critical thinking and problem solving

Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.

GQ3 Oral and written communication

Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.

GQ4 Information and digital literacy

Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.

GQ5 Inventiveness

Generating novel ideas and solutions.

GQ6 Cultural competence

Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.

GQ7 Interdisciplinary effectiveness

Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.

GQ8 Integrated professional, ethical, and personal identity

An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.

GQ9 Influence

Engaging others in a process, idea or vision.

Outcome map

Learning outcomes Graduate qualities
GQ1 GQ2 GQ3 GQ4 GQ5 GQ6 GQ7 GQ8 GQ9
Changes to the overall unit structure and review of advanced project has occurred.

More information can be found on Canvas.

Additional costs

There are no additional costs for this unit.

Work, health and safety

Students are required to review X-lab safety guidelines before completing the practical. This will be available on Canvas.

Students are reuqired to provide their own lab coat and safety glasses when attending the practical.

Disclaimer

The University reserves the right to amend units of study or no longer offer certain units, including where there are low enrolment numbers.

To help you understand common terms that we use at the University, we offer an online glossary.