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Resources

Sydney Clinical Trials Centre
Excellence in Trials. Impact in Health.

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  • https://www.sydney.edu.au/medicine-health/our-research/research-centres/sydney-clinical-trials-centre/our-research.html Our research

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Our resources support clinicians, researchers, patients, and the broader community to engage with clinical trials and apply research in practice. From tools that support clinical decision-making, to systems that enable high-quality trial delivery, and accessible information for patients and families, our resources reflect the breadth of our expertise across the clinical trials lifecycle.

Each resource is grounded in robust methodology and real-world experience, ensuring it is reliable, practical, and relevant. We invite you to explore the resources available to support informed decisions, strengthen research, and improve health outcomes through high-quality clinical trials.

Resources for the public

Our public resources are designed to help patients, families, and the wider community understand clinical trials and their role in improving health outcomes. Here you can find information on what clinical trials are, why they are important, and what it means to take part. These resources also highlight how consumers are involved in shaping trials, ensuring research reflects real-world needs and priorities. Whether you are considering participation, supporting someone involved in a trial, or simply looking to learn more, these resources offer a starting point to engage with clinical research and its impact on patient care.

A clinical trial is a type of research study that helps doctors and researchers find better ways to prevent, diagnose, and treat health conditions. Clinical trials may test new medicines, devices, or ways of delivering care, or they may look at how existing treatments can be used more effectively. These studies help answer important questions, such as which treatments work best, what the benefits and risks are, and how care can be improved for different patients.

Clinical trials are carefully designed and must follow strict safety and ethical guidelines. Before deciding to take part in a trial, potential participants are given information about the trial and the opportunity to ask questions. Participation is voluntary. Trials are usually run through hospitals or health services. Clinical trials play an essential role in advancing medical knowledge and have led to many improvements in patient care, helping people live longer and healthier lives.

Joining a clinical trial means taking part in research that aims to improve healthcare. Taking part in a clinical trial is usually offered through hospitals or healthcare providers your doctor or specialist is the best person to speak to if you are interested in taking part. They can help you understand whether a trial may be suitable for you and explain the potential benefits and risks.

Each clinical trial has specific eligibility criteria, such as age, health condition, or treatment history, so not everyone will be able to participate. If you are eligible, you will be given clear information about the study, including what is involved, and you will need to provide informed consent before joining.

Taking part in a clinical trial is always voluntary. You can choose to stop at any time. Participants are not usually paid, but some costs may be reimbursed. You can also explore opportunities through the Australian New Zealand Clinical Trials Registry (ANZCTR) or discuss options with your healthcare team to find trials that may be right for you.

Watch what LIPID trial participant, Kenneth O'Loughlin, thinks about trials.

Resources for researchers

Our researcher resources support the delivery of our trials.

High-quality clinical trials rely on high-quality data. At the Sydney Clinical Trials Centre (CTC), we design, capture, and manage trial data through secure, robust systems that support accurate data collection, monitoring, and analysis across the research lifecycle.

Our trial data systems enable authorised users to access study-specific platforms for recruitment, randomisation, electronic case report forms (eCRFs), patient-reported outcome measures (PROMs), drug-kit allocation, and training materials. Each trial may use one or multiple systems, depending on study requirements. Access is restricted to approved users, with all activity monitored to ensure data integrity, security, and compliance with regulatory standards.

Please select your trial or training system from the A-Z list

Need help?  For login issues or password resets, please contact your CTC Trial Coordinator. For further information about our systems or clinical data management at the CTC, or a quote on your data related needs, please contact our team at ctc.enquiry@sydney.edu.au

Our systems support the reliable and efficient allocation of participants and treatments within clinical trials. Designed and managed by our biostatistics and data teams, these systems ensure accuracy, consistency, and transparency in trial delivery. Our trials use a secure, web-based system for participant randomisation and drug kit allocation. Authorised users access these systems through links provided for each study. Depending on the trial, systems may be configured to support different study requirements and workflows. Access to all randomisation systems is restricted to approved users only. All activity is logged and monitored to ensure data integrity, traceability, and compliance with regulatory standards.

Please select your trial from the list below to access the relevant system.

Need help?  For access or technical issues, contact your Trial Coordinator in the first instance. If further assistance is required, please contact the CTC Biostatistics team at ctc.randostats@sydney.edu.au.

Trial Name Live Systems Training / Test Systems
ENDO3 Randomisation training / test
SUCCESS Randomisation training / test

CTC Talks is our seminar series showcasing the depth and breadth of clinical trials expertise at the CTC and among our collaborators.

Register and view our past recordings here.

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Resources for clinicians

Our clinician resources support evidence-based decision-making by translating clinical trial findings into practical tools for patient care. Drawing on our research findings, we develop resources that assist with risk assessment, prognostication, and decision-making about treatment in routine clinical practice outside of clinical trials. These tools are grounded in high-quality data and robust statistical methods, ensuring reliable and meaningful results.

These resources are intended to support clinical judgement, not replace it. Results from these tools should be considered together with each individual patient’s situation, circumstances, and preferences.

Cancer Type Tool    Description    
Advanced Cancer Three Scenarios for Survival Estimate and explain prognosis with typical, best-case, and worst-case scenarios for expected survival time in advanced cancer
Breast Cancer

Advanced Breast Cancer Online Tool

Prognosticate survival in women with advanced breast cancer receiving first-line chemotherapy
Colorectal Cancer ARCAD Advanced Colorectal Nomogram Estimate prognosis in patients with metastatic colorectal cancer about to commence first line systemic therapy
GIST

Advanced GIST Online Tool (PFS)

Advanced GIST Online Tool (OS)

Prognosticate progression-free survival decisions in patients with metastatic gastrointestinal stromal tumour (GIST) treated with imatinib
Ovarian Cancer BRCA-Mutation Positive Platinum Sensitive Recurrent Ovarian Cancer Online Tool Estimate prognosis of progression-free survival outcomes in patients with BRCA mutation positive platinum-sensitive recurrent ovarian cancer about to commence with maintenance olaparib therapy
Ovarian Cancer

Platinum Resistant Recurrent Ovarian Cancer Online

Prognosticate overall survival outcomes in patients with platinum resistant recurrent ovarian cancer treated with chemotherapy
Ovarian Cancer

Recurrent Ovarian Cancer (PFS)

Recurrent Ovarian Cancer (OS)

A tool for researchers and health care professionals to prognosticate progression free survival decisions in patients with recurrent ovarian cancer treated with platinum based chemotherapy.
Ovarian Cancer

Prognosticate progression-free survival outcomes in patients with BRCA mutation positive platinum-sensitive recurrent ovarian cancer

A tool for health care professionals and researchers to prognosticate progression-free survival outcomes in patients with BRCA mutation positive platinum-sensitive recurrent ovarian cancer about to commence with maintenance olaparib therapy
Ovarian Cancer Prognosticate overall survival for patients with advanced ovarian cancer following response to first-line chemotherapy A tool to prognosticate overall survival outcomes in patients with newly diagnosed ovarian cancer about to commence with maintenance olaparib and bevacizumab or bevacizumab monotherapy

Condition Tool Description
Type 2 diabetes. Diabetic Retinopathy Retinopathy Risk Calculator Estimate the probability of sight-threatening diabetic retinopathy (STDR) in 5 yrs
Type 1 diabetes. Diabetic Retinopathy Retinopathy Screening Visit Frequency Calculate optimal eye screening intervals for youth with Type 1 diabetes
Type I Diabetes

Insulin sensitivity calculator

Calculator of estimated insulin sensitivity (eIS) in Type 1 diabetes
Type I Diabetes Partial clinical remission of Type 1 diabetes calculator Calculator to estimate probability of partial clinical remission of adult-onset Type 1 diabetes at 12 months post-diagnosis

Condition Tool Description
Socio-economic tools Socio-economic indices comparison in Australia Online tool for cross-sectional and longitudinal comparison of socio-economic status indices, based on postcodes, in Australia.

Contact us

Mailing address
Sydney Clinical Trials Centre
ABN 15 211 513 464
Locked Bag 77
Camperdown NSW 1450

Physical locations
Lifehouse Building
Level 6, 119-143 Missenden Road
Camperdown NSW 2050

RPA Gloucester House
Level 6, Gloucester House Drive
Camperdown NSW 2050