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Topological Organisation of Deep Brain Structures

Summary

Subcortical brain structures play a central role in the integration and modulation of neural signalling from the brainstem to cortical mantle. Advances in static and dynamic high field neuroimaging now allow unprecedented precision in delineating the structure and function of the pathways and sub-nuclei of deep-brain structures, notably key brain relay hubs such as the thalamus. This project aims to use novel multi-modal neuroimaging techniques to define the functional and neuromodulatory role of deep brain sub-nuclei in large scale brain networks and cognition.

Supervisor

Dr Sicong Tu.

Research location

Camperdown - Brain and Mind Centre

Synopsis

This project uses a multi-modal neuroimaging approach to map out the topology of fine-grained deep brain sub-structures, their connections, and function in healthy ageing and neurodegeneration. Experimental techniques and expertise that will be taught as part of the project include:

  • Composite structural imaging
  • Brain atlas creation
  • Functional MRI
  • Diffusion MRI
  • MR spectroscopy.

Additional information

Sub-components of the project are suitable for prospective Honours students.

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Opportunity ID

The opportunity ID for this research opportunity is 2990

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