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TARGETING THE BRAIN VASCULATURE AS A TREATMENT FOR CEREBRAL TYPE I INTERFERONOPATHIES

Abnormal blood vessels are feature of cerebral type I interferonopathies. Discover how the endothelial cells that line the brain’s blood vessels contribute to disease in patie more...

Supervisor(s): Hofer, Markus (Dr)

THE PATHOGENIC AND PROTECTIVE EFFECTS OF MICROGLIA IN CEREBRAL CYTOKINOPATHIES

Microglia are the primary immune cells of the brain and have the potential to both protect and contribute to neurological disease. Explore the molecular mechanisms that microglia us more...

Supervisor(s): Hofer, Markus (Dr)

HOW DIFFERENT CELL TYPES OF THE BRAIN CONTRIBUTE TO CEREBRAL CYTOKINOPATHIES

The brain consists of a large number of different cell types, including neurons, astrocytes, oligodendrocytes, microglia and endothelial cells. Discover how these different cell typ more...

Supervisor(s): Hofer, Markus (Dr)

EFFECTS OF TYPE I INTERFERONS IN CHRONIC VIRAL INFECTIONS

When type I interferon signalling is impaired, infection with lymphocytic choriomeningitis virus results in chronic infection and dysfunctional CD8+ T cell function. Investigate how more...

Supervisor(s): Hofer, Markus (Dr)

Optimising ecosystem services for fishes from restored oyster reefs

Oyster reefs have declined precipitously over the past 100 years. This project is looking at restoration options which provide the maximum ecosystem services in a cost effective man more...

Supervisor(s): Figueira, William (Associate Professor), Bugnot, Ana (Dr)

Understanding drivers of tropical fish range expansions

Warming oceans from climate change is driving an increase in the occurrence of tropical fishes in temperate latitudes. While we are beginning to understand the factors that may limi more...

Supervisor(s): Figueira, William (Associate Professor)

Assessing the range expansion of hard corals into temperate waters

The subtropical endemic coral Pocillopora alicia has recently been observed off the coast of Sydney. This project will seek to document the extent of coverage of this species and to more...

Supervisor(s): Figueira, William (Associate Professor), Sommer, Brigitte (Dr)

Conserved Regulatory Genes in Neurodevelopment

The present project aims to utilize the promising combination of 3D organoid technology and CRISPR genome editing, which will allow us to examine the roles of several conserved gene more...

Supervisor(s): Neely, Greg (Professor)

Investigating disease in threatened Australian wildlife

This PhD project aims to investigate disease in threatened Australian wildlife using conservation immunogenetics, and forms part of an ARC Discovery project entitled “Marsupia more...

Supervisor(s): Belov, Katherine (Kathy) (Professor)

The nutritional geometry of non-alcoholic fatty liver disease, cardio-metabolic health and lifespan

The global epidemic of obesity and type 2 diabetes (T2D) has been linked to increased consumption of ‘western diets’ containing an abundance of processed foods rich in s more...

Supervisor(s): Simpson, Stephen (Professor), Wali, Jibran (Dr)