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Medicinal Chemistry and Biology - Development of Novel Anti-Tumour Agents for Cancer Treatment

This project is involved in the exciting development of novel drugs for the treatment of cancer and other conditions. more...

Supervisor(s): Richardson, Des (Professor)

Investigating the links between telomerase and the DNA damage response in cancer cells

The ribonucleoprotein enzyme telomerase counteracts telomere shortening in a majority of cancers, allowing for unlimited cell division. Most normal cells do not express telomerase, more...

Supervisor(s): Bryan, Tracy (Professor)

Towards a cure for Type I diabetes mellitus

Transfect a lentivirus construct expressing an immunosuppressive peptide in islet cells for the treatment of diabetes type I more...

Supervisor(s): Manolios, Nicholas (Professor), Logan, Grant (Dr)

Prevalence and impact of incorrect cancer research publications targeting the functions of human genes

This PhD project analyses the reliability of the cancer research literature, from which new cancer biomarkers and molecular targets are derived. more...

Supervisor(s): Byrne, Jennifer (Professor)

Search for a cause: the role of astrocytes in the early pathology of Parkinson's disease

The projects in our lab are directed towards finding the cause of Parkinson’s Disease.  In particular we want to know what is the nature of the mechanism that sets the ne more...

Supervisor(s): Allbutt, Haydn (Dr)

Phosphoproteomics in early T-cell signalling

Using phospho-proteomics to understand T-cell signalling/signal transduction. more...

Supervisor(s): Manolios, Nicholas (Professor)

THE USE OF MARIJUANA AND/OR ENDOCANNABINOID OILS FOR THE TREATMENT OF OSTEOARTHRITIS (OA)

Pre-clinical studies for the effects of CBD and analogues for the treatment of osteoarthritis more...

Supervisor(s): Manolios, Nicholas (Professor), Arnold, Jonathon (Associate Professor)

How do gingipains recognise their host cell targets?

Porphyromonas gingivalis is a gram-negative, rod-shaped anaerobic pathogenic bacterium that found in the oral cavity. more...

Supervisor(s): Collyer, Charles (Associate Professor)

REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)

Patient preferences and willingness to pay for genomic information in cancer and cardiovascular disease

It is not clear how people value genetic or genomic health information, and traditional economic evaluation may not capture the full benefit of this service. This PhD will examine p more...

Supervisor(s): Morton, Rachael (Associate Professor)