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Characterising insulin secretory granules as a function of age

In β-cells, insulin is stored in secretory granules (SGs). Upon stimulation, these SGs deliver insulin to the bloodstream. It is known that SGs exist in two functionally distin more...

Supervisor(s): Kebede, Melkam (Dr)

Investigating the cognitive and psychological consequences of sports-related mild traumatic brain injury (mTBI)

Mild traumatic brain injury (mTBI; also known as concussion) occurs frequently in contact sports due to direct hits or rotational acceleration of the head. While most people recover more...

Supervisor(s): Grieve, Stuart (Professor)

Resuscitation monitors for the neonatal intensive care uni (NICU)

Development (design and fabrication) of a portable and wireless lung function monitor for the resuscitation of neonates. The project will involve embedded electronics, Labview progr more...

Supervisor(s): McEwan, Alistair (Professor)

Faraday Rotation in Organic Semiconductors

Society's over-reliance on information exchange around the world hinges critically on ultrafast data communication using light signals.  Modern optical data communication works more...

Supervisor(s): Lakhwani, Girish (Dr)

Design and synthesis of selective anion receptors to facilitate transmembrane anion transport in epithelial cells

CF is a recessive genetic condition that results from the dysregulation of anion transport through the cystic fibrosis transmembrane regulator anion channel in epithelial cell membr more...

Supervisor(s): Gale, Philip (Professor)

Randomized controlled trial of epiretinal membrane surgery

Randomized controlled trial of epiretinal membrane surgery more...

Supervisor(s): Simunovic, Matthew (Associate Professor)

Characterising changes in a proteome of islets and islet cell types during progression to type 2 diabetes

Characterizing changes in a proteome through pathogenesis of diseases can provide unparalleled insights into the mechanisms underpinning disease. In this project, using flow cytomet more...

Supervisor(s): Kebede, Melkam (Dr)

Sorting proinsulin into secretory vesicles

Reduction in glucose-stimulated mature insulin secretion and increased constitutive and regulated secretion of proinsulin are characteristics of β-cell failure. This may be due more...

Supervisor(s): Kebede, Melkam (Dr)

CRF-dopamine interactions in chronic stress

The project will focus on the interactions between CRF and the dopaminergic nuclei of the ventral midbrain and their role in modulating behaviour selection. more...

Supervisor(s): Mor, David (Dr)

Inverse Methods for Characterising Hydraulic Properties of Soils Under Unsaturated Conditions

New indirect methods for estimating material properties of partially saturated soils are developed based on infiltration tests and inversion of multi-phase hydro-mechanical equation more...

Supervisor(s): El-Zein, Abbas (Professor)