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Identifying new drivers of lung cancer

This project will identify and investigate novel genes mutated in a Kras-induced mouse model of lung adenocarcinoma more...

Supervisor(s): Howell, Viive (Dr), Colvin, Emily (Dr)

Gene function and RNA processing in gut endoderm development

This project aims to unravel the impact of RNA processing on the function the targets of a RNA binding protein in the development of the embryonic gut and the associated organs. more...

Supervisor(s): Fossat, Nicolas (Dr), Tam, Patrick (Professor)

Pathways to therapies in blinding genetic retinal eye diseases

In this project, novel disease genes and variants are identified that cause blinding retinal eye diseases. Cellular, gene editing, proteomic and animal model approaches are taken to more...

Supervisor(s): Jamieson, Robyn (Associate Professor)

Targeting Regulatory T Cells for the Treatment of Autoimmune Renal Disease

This project will investigate the role of regulatory T cells for the treatment of autoimmunity kidney disease.    more...

Supervisor(s): Alexander, Stephen (Professor), Wang, Yuan Min (Dr)

Gene therapy for genetic and acquired diseases of the liver and haematopoietic system.

We are working on developing new therapies for the treatment of genetic and acquired diseases of the liver and haematopoietic system. The Gene Therapy Research Unit has a diverse se more...

Supervisor(s): Alexander, Ian (Professor), Ginn, Samantha (Dr), Logan, Grant (Dr)

Discovery and validation of new ceramide synthase inhibitors to treat metabolic disease

Ceramide synthase enzyme isoforms 1, 5, and 6, are heavily implicated as drivers of obesity, insulin resistance, and diabetes. Targeting these enzymes is expected to yield new thera more...

Supervisor(s): Don, Anthony (Associate Professor), Qi, Jacob (Dr)

Pharmacological targeting of sphingosine 1-phosphate receptors to promote remyelination in Alzheimer’s disease and multiple sclerosis

In this project you will investigate a new molecular pathway that is required for normal myelin formation, and the therapeutic potential of targeting this pathway to promote remyeli more...

Supervisor(s): Don, Anthony (Associate Professor)

The role of key driver genes in the pathogenesis of acute renal allograft rejection

This is a PhD project. The successful applicant will be top up scholarship. This study will lead to publish high quality of papers and apply a new NHMRC project grant. more...

Supervisor(s): O'Connell, Philip (Professor), Hu, Min (Dr)

Identifying the causes of fibrosis after kidney transplantation

This is a PhD project. The successful applicant will be top up scholarship. This study will lead to publish high quality of papers and apply a new NHMRC project grant. more...

Supervisor(s): O'Connell, Philip (Professor)

Using Gene editing to cure genetic neurological disorders

This project is an opportunity for a PhD student who is interested in genetic disorders of the brain and who is prepared to work at the cutting edge of technology. Genetic neurologi more...

Supervisor(s): Gold, Wendy (Dr)