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Developing small molecules that enhance PCSK9/AnxA2 interaction to inhibit PCSK9 and elevate LDLR levels

Statins to decrease low density lipoprotein cholesterol (LDL-C) are a cornerstone to prevent and treat cardiovascular events. However, inadequate dose response, resistance, and seri more...

Supervisor(s): Grewal , Thomas (Associate Professor)

Nutrient regulation of the stem cell compartment

Australia is among the countries with the fastest growing rates of overweight and obesity, which by 2025 will affect >70% of the population. Chronic diseases linked to obesity in more...

Supervisor(s): George, Jacob (Professor)

LDL-cholesterol controls the role of integrins in cancer cell migration

This project explores the role of LDL-cholesterol in integrin trafficking and signalling, which is relevant for cancer cell migration. more...

Supervisor(s): Grewal , Thomas (Associate Professor)

Pilot Efficacy Trial of Electrical Stimulation Cycling Exercise for Advanced Multiple Sclerosis

Multiple sclerosis (MS) is an incurable disease of the central nervous system that typically affects people in their 30's and 40's. MS results in slowly increasing muscle paralysis, more...

Supervisor(s): Fornusek, Che (Dr)

Pilot Study of Progressive Resistance Training for Sedentary Adults with Charcot-Marie-Tooth

This project is for a resistance training program in persons with Charcot-Marie-Tooth (CMT). CMT is the most frequently inherited peripheral neuropathy affecting around 1 in 2500 pe more...

Supervisor(s): Fornusek, Che (Dr)

Determining Value and Impact of the CPC through stakeholder analysis

The Charles Perkin Centre (CPC) officially launched in 2014 is the central hub and flagship of Sydney University to provide collaboration for interdisciplinary research amongst var more...

Supervisor(s): Chung, Kenneth (Dr)

Prevention of cardiac side effects of cancer treatment

This project will investigate a novel drug combination therapy that has potential benefits in cancer treatment induced heart failure by targeting Na+-K+ pump function. more...

Supervisor(s): Liu, Chia-chi (Dr), Ramussen, Helge (Professor)

The HAMLET molecular species with anticancer properties

We are interested to determine how the anti-cancer properties of this family of molecules can be translated into cancer treatment. We believe there may be a delivery system which n more...

Supervisor(s): Church, W Bret (Dr)

Investigation of the Demands of Participation in Physical Disability Rugby League

Physical Disability Rugby League is a sport that was created in Sydney to allow persons with physical disability to play league (https://www.youtube.com/watch?v=yV04gbXUURo). Curren more...

Supervisor(s): Fornusek, Che (Dr)

James Millner PHD Scholarship in Pharmacy

James Millner AM graduated from Pharmacy at the University of Sydney in 1947 and after returning home from being a prisoner of war during World War 2, he joined the family business, more...

Supervisor(s): Bero , Lisa (Professor)