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Analysis of Human Responses to Intermittent Fasting

Analysis of human samples generated from intervention-based clinical trials of intermittent fasting. Our aim is to understand the molecular mechanisms mediating the beneficial pheno more...

Supervisor(s): Larance, Mark (Dr)

The global analysis of liver protein complexes during the response to intermittent fasting

In animals, short periods of nutrient deprivation, such as intermittent fasting, have been shown to provide benefits with regard to cancer risk/treatment and ageing. Our aims are to more...

Supervisor(s): Larance, Mark (Dr)

Improving weight loss outcomes via intermittent very low energy diets

This project aims to determine whether intermittent use of a very low energy diet (VLED) produces greater, more efficient, or longer lasting weight loss than continuous VLED use. more...

Supervisor(s): Salis, Amanda (Associate Professor)

CHARACTERISATION OF ERUSIOLIN - A NEW PEPTIDE HORMONE

In this project we aim to characterise the function of a new gut-derived peptide we have discovered in human plasma, named erusiolin, which we hypothesise plays a role in appetite r more...

Supervisor(s): Larance, Mark (Dr)

Concord Health and Ageing in Men Project (CHAMP)

CHAMP is a large epidemiological study of ageing in men, with a particular focus on Alzheimer’s disease, osteoporosis and urinary incontinence. more...

Supervisor(s): Cumming , Robert G (Professor)

A study to investigate the efficacy of dexamphetamine compared to placebo for treating obesity complicated by obstructive sleep apnoea

The project represents a new approach to the pharmacological treatment of obesity. It uses dexamphetamine but unlike most drug trials using appetite suppressants, the focus is on th more...

Supervisor(s): Poulton, Alison (Dr)