Unit outline_

CPAT3202: Pathogenesis of Human Disease 2

Semester 2, 2025 [Normal day] - Camperdown/Darlington, Sydney

The Pathogenesis of Human Disease 2 unit of study will provide a theoretical and practical background to the scientific basis of the pathogenesis of systemic diseases. Extending upon the knowledge gained from CPAT3201, areas covered in practical modules include the response of renal, cardiovascular, neurological and accessory digestive systems to disease. In the practical modules, these areas will be expanded to include specimen evaluation on a macroscopic and microscopic basis. The aims of the course are: - To provide students opportunities to understand how different organ systems react to injury through the application of basic concepts of disease processes. - To equip students with skills appropriate for careers in the biomedical sciences and for further training in research or professional degrees. At the end of the course students will: - Be able to describe, synthesise and present information on disease pathogenesis to a scientific audience. - Transfer problem-solving skills to novel situations related to disease pathogenesis. - Understand basic investigative techniques for disease detection in pathology. - Acquired practical skills in the use of a light microscope. - Evaluate diseased tissue at the macroscopic and microscopic level. Compile and maintain a detailed scientific lab notebook. This unit of study is appropriate for those who intend to proceed to Honours research, to postgraduate studies such as Medicine or to careers in biomedical areas such as hospital science. Enquiries should be directed to melanie.white@sydney.edu.au.

Unit details and rules

Academic unit Department of Medical Sciences
Credit points 6
Prerequisites
? 
12 credit points from {(IMMU2X11 or IMMU2101 or MEDS2004 or MIMI2X02) or [(MEDS2004 or MIMI2X02) and (MEDS2001 or MEDS2003 or PHSI2X07)] or MEDS201X}
Corequisites
? 
None
Prohibitions
? 
CPAT3902
Assumed knowledge
? 

Sound knowledge of biology through meeting pre-requisites

Available to study abroad and exchange students

Yes

Teaching staff

Coordinator Melanie White, melanie.white@sydney.edu.au
The census date for this unit availability is 1 September 2025
Type Description Weight Due Length Use of AI
Written exam
? 
Final exam
Extended answer questions covering all modules delivered
40% Formal exam period 2 hours AI prohibited
Outcomes assessed: LO1 LO2 LO3 LO4 LO5
Portfolio or journal Submission of practical workbook
EAQ with a microscopic and macroscopic evaluation of diseases
10% Multiple weeks approx 500 words AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4 LO5
Contribution Museum Peer Discussions
Students contribute to collaborative learning (peer-teaching) with supporting documents submitted to Canvas
20% Multiple weeks 20 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4 LO5
In-class quiz Quiz 1
MCQ - covering the CVD and Neurological modules
10% Week 06
Due date: 09 Sep 2025 at 13:00
30 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4
In-class quiz Quiz 2
MCQ - covering the Hepatobiliary diseases and Haematopathology modules
10% Week 10
Due date: 14 Oct 2025 at 13:00
30 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4
In-class quiz Quiz 3
MCQ - covering the Endocrinopathies module and object classification (histopathology and macroscopic specimens)
10% Week 13
Due date: 04 Nov 2025 at 13:00
30 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4

Assessment summary

Practical workbooks: One workbook is available per disease module. All questions must be attempted in short answer format to be considered a completed submission. Submissions must be made before the relevant due date. 

In-class quiz: The content to be examined will include all relevant material (lectures, practicals) for CPAT3202 up until (and including) the week before the exam.

Museum Peer Discussions: Students will engage in peer learning in fortnightly museum (macroscopic) practicals. Submission types include discussion posts and slide decks. Submissions must be made before the relevant due date. 

Final Exam: The exam is comprised of extended answer questions.

Detailed information for each assessment can be found on Canvas.

Assessment criteria

The University awards common result grades, set out in the Coursework Policy 2014 (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

For more information see sydney.edu.au/students/guide-to-grades.

 

For more information see guide to grades.

Use of generative artificial intelligence (AI)

You can use generative AI tools for open assessments. Restrictions on AI use apply to secure, supervised assessments used to confirm if students have met specific learning outcomes.

Refer to the assessment table above to see if AI is allowed, for assessments in this unit and check Canvas for full instructions on assessment tasks and AI use.

If you use AI, you must always acknowledge it. Misusing AI may lead to a breach of the Academic Integrity Policy.

Visit the Current Students website for more information on AI in assessments, including details on how to acknowledge its use.

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

  • Deduction of 5% of the maximum mark for each calendar day after the due date.
  • After ten calendar days late, a mark of zero will be awarded.

This unit has an exception to the standard University policy or supplementary information has been provided by the unit coordinator. This information is displayed below:

Late assignments that have not been granted an extension will attract a penalty of 5% of the maximum mark per day late, including weekend days (e.g. if the assignment is worth 40 marks, the penalty is 2 marks per day late). Assignments submitted over 10 days late will be marked as zero (0).

Academic integrity

The University expects students to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.

Our website provides information on academic integrity and the resources available to all students. This includes advice on how to avoid common breaches of academic integrity. Ensure that you have completed the Academic Honesty Education Module (AHEM) which is mandatory for all commencing coursework students

Penalties for serious breaches can significantly impact your studies and your career after graduation. It is important that you speak with your unit coordinator if you need help with completing assessments.

Visit the Current Students website for more information on AI in assessments, including details on how to acknowledge its use.

Simple extensions

If you encounter a problem submitting your work on time, you may be able to apply for an extension of five calendar days through a simple extension.  The application process will be different depending on the type of assessment and extensions cannot be granted for some assessment types like exams.

Special consideration

If exceptional circumstances mean you can’t complete an assessment, you need consideration for a longer period of time, or if you have essential commitments which impact your performance in an assessment, you may be eligible for special consideration or special arrangements.

Special consideration applications will not be affected by a simple extension application.

Using AI responsibly

Co-created with students, AI in Education includes lots of helpful examples of how students use generative AI tools to support their learning. It explains how generative AI works, the different tools available and how to use them responsibly and productively.

Support for students

The Support for Students Policy reflects the University’s commitment to supporting students in their academic journey and making the University safe for students. It is important that you read and understand this policy so that you are familiar with the range of support services available to you and understand how to engage with them.

The University uses email as its primary source of communication with students who need support under the Support for Students Policy. Make sure you check your University email regularly and respond to any communications received from the University.

Learning resources and detailed information about weekly assessment and learning activities can be accessed via Canvas. It is essential that you visit your unit of study Canvas site to ensure you are up to date with all of your tasks.

If you are having difficulties completing your studies, or are feeling unsure about your progress, we are here to help. You can access the support services offered by the University at any time:

Support and Services (including health and wellbeing services, financial support and learning support)
Course planning and administration
Meet with an Academic Adviser

WK Topic Learning activity Learning outcomes
Multiple weeks Problem based learning Workshop (6 hr) LO2 LO3 LO5 LO4 LO1
Museum Specimen Drop-in Forum (3 hr) LO3 LO5
Modern approaches to pathology Seminar (4 hr) LO5 LO4
Week 01 Cardiovascular Pathology 1 Lecture and tutorial (3.5 hr) LO2 LO3 LO5 LO4 LO1
Week 02 Cardiovascular Pathology 2 Lecture (2 hr) LO2 LO3 LO1
Cardiovascular Pathology 2 Practical (2 hr) LO2 LO3 LO5 LO4
Week 03 Cardiovascular Pathology 3 Lecture and tutorial (3.5 hr) LO2 LO3 LO5 LO4 LO1
Week 04 Neurological Diseases 1 Lecture (2 hr) LO2 LO3 LO1
Neurological Diseases 1 Practical (2 hr) LO2 LO3 LO5 LO4
Week 05 Neurological Diseases 2 Lecture and tutorial (3.5 hr) LO2 LO3 LO5 LO4 LO1
Week 06 Hepatobiliary Diseases 1 Lecture (2 hr) LO2 LO3 LO1
Hepatobiliary Diseases 1 Practical (2 hr) LO2 LO3 LO5 LO4
Week 07 Hepatobiliary Diseases 2 Lecture and tutorial (2.5 hr) LO2 LO3 LO5 LO4 LO1
Week 08 Haematopathology 1 Lecture (2 hr) LO2 LO3 LO1
Haematopathology 1 Practical (2 hr) LO2 LO3 LO5 LO4
Week 09 Haematopathology 2 Lecture and tutorial (3.5 hr) LO2 LO3 LO5 LO4 LO1
Week 10 Endocrinopathies 1 Lecture (2 hr) LO2 LO3 LO1
Endocrinopathies 1 Practical (2 hr) LO2 LO3 LO5 LO4
Week 11 Endocrinopathies 2 Lecture and tutorial (3.5 hr) LO2 LO3 LO5 LO4 LO1
Week 12 Oral and Maxillofacial Pathology 1 Lecture and tutorial (3.5 hr) LO2 LO3 LO5 LO4 LO1
Week 13 Oral and Maxillofacial Pathology 2 Lecture (2 hr) LO2 LO3 LO1
Oral and Maxillofacial Pathology 2 Practical (2 hr) LO2 LO3 LO5 LO4

Attendance and class requirements

Students must attend at least 80% of compulsory museum and microscope practicals for this unit, per the University Coursework Policy.

Attendance is recorded and will be used to support a case for absent fail (AF) where necessary. Students found to have fraudulently recorded attendance (or provided the means to others) will be reported for academic misconduct investigation.

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Required readings

All readings for this unit can be accessed through the Reading List, available on Canvas.

  • Robbins Basic Pathology (2018) 10th Edition. Vinay Kumar, Abul K. Abbas and Jon. C. Aster

Further reading is also available through the Reading List (Canvas)

  • Robbins & Cotran Pathologic Basis of Disease (2018) 10th Edition. Vinay Kumar, Abul K. Abbas and Jon C. Aster 

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University's graduate qualities and are assessed as part of the curriculum.

At the completion of this unit, you should be able to:

  • LO1. Define and explain how different organ systems react to injury and adapt to pathology.
  • LO2. Interpret key mechanisms of pathogenic processes to synthesise original insights and predict outcomes.
  • LO3. Classify microscopic and macroscopic specimens to allow for evaluation and analysis of pathogenesis and disease.
  • LO4. Summarise and transfer problem-solving skills to predict the outcomes of novel situations related to disease pathogenesis.
  • LO5. Identify, evaluate and integrate scholarly information on disease pathogenesis for written and verbal communication to a learned audience.

Graduate qualities

The graduate qualities are the qualities and skills that all University of Sydney graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1 Depth of disciplinary expertise

Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.

GQ2 Critical thinking and problem solving

Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.

GQ3 Oral and written communication

Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.

GQ4 Information and digital literacy

Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.

GQ5 Inventiveness

Generating novel ideas and solutions.

GQ6 Cultural competence

Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.

GQ7 Interdisciplinary effectiveness

Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.

GQ8 Integrated professional, ethical, and personal identity

An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.

GQ9 Influence

Engaging others in a process, idea or vision.

Outcome map

Learning outcomes Graduate qualities
GQ1 GQ2 GQ3 GQ4 GQ5 GQ6 GQ7 GQ8 GQ9

This section outlines changes made to this unit following staff and student reviews.

In response to student feedback (2024), the timetable now features activities on three days (as opposed to five days in 2024); museum collaborative learning now includes a presubmitted question to encourage the small group discussions. Drop-in sessions are now offered weekly for students to engage with the academic team. PBLs developed in 2023 continue to be enjoyed and will be retained for 2025.

Work, health and safety

We are governed by the Work Health and Safety Act 2011, Work Health and Safety Regulation 2011 and Codes of Practice. Penalties for non-compliance have increased. Everyone has a responsibility for health and safety at work. The University’s Work Health and Safety policy explains the responsibilities and expectations of workers and others and the procedures for managing WHS risks associated with University activities.

General Laboratory Safety Rules

  • No eating or drinking is allowed in any laboratory under any circumstances 
  • A laboratory coat and closed-toe shoes are mandatory 
  • Follow safety instructions posted in laboratories 
  • In case of fire, follow instructions posted outside the laboratory door 
  • First aid kits, eyewash and fire extinguishers are located in or immediately outside each laboratory 
  • As a precautionary measure, it is recommended that you have a current tetanus immunisation. This can be obtained from University Health Service: unihealth.usyd.edu.au/

Disclaimer

The University reserves the right to amend units of study or no longer offer certain units, including where there are low enrolment numbers.

To help you understand common terms that we use at the University, we offer an online glossary.